Latent autoimmune diabetes mellitus in adults (LADA): the role of antibodies to glutamic
acid decarboxylase in diagnosis and prediction of insulin dependency
Injection of estrogens (17β - estradiol or diethylstilbestrol) into immature chicks results in a marked (30 - to 50-fold) increase in the
ornithine decarboxylase activity of oviductal homogenates within a 4 - hour period.
As can be seen in
Arginine Decarboxylase, the success of these paintings is due in part to their expression of certain aspects of Hirst's own views on art and science, and in part due to his sheer infectious love of colour.
An elevation of
decarboxylase activity was obtained in vitro when oviducts from immature chicks were incubated in the presence of estrogen.
They looked at two top autoantibodies: one directly against insulin, called IAA, and one called GADA, against the enzyme
glutamate decarboxylase, which regulates the insulin - producing beta cells in the pancreas.
The pathogen - inducible nitric oxide synthase (iNOS) in plants is a variant of the p protein of the
glycine decarboxylase complex (Retraction of vol 113, pg 469, 2003)
They also hypothesized that the
phenylacetate decarboxylase reaction provides a strategy for the bacterium to regulate its internal pH in a somewhat acidic, fermentative environment.
The Pathogen - Inducible Nitric Oxide Synthase (iNOS) in Plants Is a Variant of the P Protein of the Glycine Decarboxylase Complex
DOPA is then converted to dopamine by
DOPA decarboxylase which requires a vitamin B6 cofactor.
In 2009, Siegel the elder also came to Baker's lab for a few weeks» sabbatical, working on a three - dimensional description of
orotate decarboxylase, the enzyme he studied back in his Ph.D. days, with Justin's help.
The accumulation of cerebral 5 - hydroxytryptophan
after decarboxylase inhibition was decreased in rats maintained at arterial O2 tensions below 60 mm - Hg.
Similar stimulations were obtained when estrogen was injected into hypophysectomized or castrated rats and the uterus was examined
for decarboxylase activity.
The autoantibodies commonly produced by people with APECED include one that is a marker of type 1 diabetes, called glutamic acid
decarboxylase autoantibody (GAD).
Next, the researchers gave the flies a single dose of cocaine then monitored the activity of
tyrosine decarboxylase (TDC), an enzyme that normally shows a spike in activity after cocaine exposure.
Heterologous expression of the enzyme α -
ketoisovalerate decarboxylase (Kivd) in the unicellular cyanobacterium Synechocystis PCC 6803 results in cells producing isobutanol and 3 - methyl -1-butanol, with Kivd identified as a potential bottleneck.
Effects of tetrahydrofolate polyglutamates on the kinetic parameters of serine hydroxymethyltransferase and glycine
decarboxylase from pea leaf mitochondria
Crystal structure of a putative
oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution.
In an earlier section we discussed how the body converts glutamine to GABA using the glutamic
acid decarboxylase enzyme and the activated form of vitamin B6.
Writing about Pharmaceutical Paintings such as
Arginine Decarboxylase, he himself explained that, «I believe painting and all art should be ultimately uplifting for a viewer.
GABA is synthesized from the amino acid glutamate with the enzyme
glutamate decarboxylase (GAD) and pyridoxal phosphate (which is the activated form of vitamin B6) as the key cofactor.
Additionally, the American elder extract showed inhibition of
ornithine decarboxylase, which is an enzyme marker related to the promotion stage of cancer formation.
So Beller's team looked for just such a cluster of genes among the candidate genes in the toluenemaking sewage sample, and they found the GRE
phenylacetate decarboxylase (PhdB) and its activator, PhdA.
Extensive genetic detective work led them to a mutation in a gene called HDC, which encodes L -
histidine decarboxylase, an enzyme involved in the production of histamine, a signaling molecule with a wide variety of roles throughout the body.
In particular, the ones involved include Tyrosine hydroxylase (TH) and
DOPA decarboxylase (DDC)(9).
Li, Bennett and Fouad found that the AADC (Aromatic l - amino acid
decarboxylase) enzyme that converts dietary amino acids into trace amines was upregulated in specialized cells called pericytes that wrap capillaries.
Patients with LADA — a form of autoimmune type 1 diabetes in adulthood — can be distinguished from patients with non-autoimmune type 2 diabetes by means of the antibody reaction affinity to the enzyme glutamic acid
decarboxylase (GAD).
A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, a polyA sequence, and an frt - flanked neo cassette into the 3» untranslated region (after the translational termination site) of the glutamic acid
decarboxylase 2 locus (Gad2) on chromosome 2.
This is a survey of the distribution, form, and proportion of neurons immunoreactive for gamma - aminobutyric acid (GABA) or glutamic acid
decarboxylase (GAD) in cat primary auditory cortex (AI).
Catecholaminergic neurons containing GABA - like and / or glutamic acid
decarboxylase - like immunoreactivities in various brain regions of the rat
Evaluation of the use of malic acid
decarboxylase - deficient starter culture in NaCl - free cucumber fermentations to reduce bloater incidence — Y. Zhai, Journal of Applied Microbiology
Kosaka T, Kosaka K, Hataguchi Y, Nagatsu I, Wu JY, Ottersen OP, Storm - Mathisen J, Hama K (1987) Catecholaminergic neurons containing GABA - like and / or glutamic acid
decarboxylase - like immunoreactivities in various brain regions of the rat Exp Brain Res, 66 (1), 191 - 210 PubMed 2884126
In Stiff Person Syndrome, which is a rare autoimmune disease in the central nervous system with autoantibodies targeting glutamic acid
decarboxylase (GAD65), the humoral autoimmune response was shown to consist of a Rituximab - sensitive part rapidly cleared after treatment, and a Rituximab - resistant part from long - lived and persistent plasma cells acting as a reservoir for secretion of autoantibodies.
Regulation of the expression of human ornithine
decarboxylase gene and ornithine decarboxylase promoter - driven reporter gene in transgenic mice
Human brain interneurons express the enzymes tyrosine hydroxylase (TH) and DOPA (3,4 - dihydroxyphenylalanine)
decarboxylase (DDC).
Additionally, if an individual has glutamic acid
decarboxylase (an enzyme) antibodies, the body destroys the enzyme that converts glutamic acid to GABA.
Additionally, some people have antibodies against the glutamic acid
decarboxylase (GAD) enzyme, which is involved in the release of insulin from the pancreas.
Although larger studies are needed, this deficiency in glutamic acid
decarboxylase could be explained by the presence of antibodies against glutamic acid decarboxylase 65 (GAD65) which has been detected in the serum of children with autism [12].
Moreover, children with autism are also deficient in glutamic acid
decarboxylase, an enzyme involved in converting glutamate to GABA (γ - Aminobutyric acid).
GAD stands for glutamic acid
decarboxylase, an enzyme that triggers production of the brain's primary calming chemical, called GABA.
For example, mercury increases extracellular levels of the excitatory neurotransmitter glutamate, thus overactivating glutamate receptors on cell surfaces.42 The amplification of glutamate is further exacerbated by mercury's inhibition of the calming neurotransmitter GABA.37 Mercury blocks GABA receptors, disproportionately destroys GABA - producing Purkinje neurons and impairs glutamate
decarboxylase (GAD), the enzyme responsible for converting glutamate to GABA.
Via an enzyme called L - amino acid
decarboxylase.
Testing for antibodies against glutamic acid
decarboxylase and antinuclear antibodies was negative.
Recently, a radioimmunoprecipitation assay was developed to detect antibodies to recombinant canine glutamic acid
decarboxylase and insulinoma antigen - 2 (84,85).
The endogenous synthesis of taurine is limited by the low activities of cysteine dioxygenase and cysteinesulphinic acid decarboxylase
Executed in 1994, Arginine
Decarboxylase is one of the largest of Damien Hirst's early and celebrated Spot Paintings.
Nonetheless, those neatly stacked products gave a sense of reason and purpose that was taken up in the pill - like progression of coloured circles in Arginine
Decarboxylase.
Phrases with «decarboxylase»