As Goldberg said in a Philadelphia Inquirer story about the HCV kidney transplant trial mentioned above, «last year, about 12,000 people in the U.S. got
a deceased donor kidney transplant.
«Patients on dialysis are living longer and equally positive, survival rates have steadily improved among recipients of both living and
deceased donor kidney transplants.»
Upon receiving
deceased donor kidneys from African Americans with two APOL1 renal - risk variants, transplant recipients experience earlier allograft failure.
Not exact matches
By passively cooling
deceased organ
donor body temperature by approximately two degrees from normal body temperature, researchers saw an overall nearly 40 percent increase in the successful function of donated
kidneys after surgery.
Mild hypothermia in
deceased organ
donors significantly reduces delayed graft function in
kidney transplant recipients when compared to normal body temperature, according to UC San Francisco researchers and collaborators, a finding that could lead to an increase in the availability of
kidneys for transplant.
«Mild hypothermia in
deceased organ
donors improves organ function in
kidney transplant: Finding could increase overall organ availability.»
Slight changes to the system for allocating
deceased -
donor kidneys could result in higher rates of organ procurement and lead to more
kidney transplants across the country, according to new research co-authored by an Indiana University Kelley School of Business professor.
No wonder that those needing a
kidney vastly exceed the number of
kidneys available from
deceased donors.
Kidney dialysis is often used as a treatment, but the best long - term solution is transplant, usually from a recently -
deceased donor.
And in another Penn project, researchers are studying the potential benefits for some patients to accept
kidney transplants from
deceased diabetic
donors, rather than remaining on the organ transplant list for a «lower risk» transplant.
To understand why these
kidneys are not being used, with the goal of improving
kidney utilization, reducing wait times, and providing transplants to more patients, a team led by Sumit Mohan, MD, MPH and S. Ali Husain, MD, MPH (Columbia University Medical Center) analyzed information on
deceased donors from whom both
kidneys were procured but only one was transplanted from 2000 - 2015.
While most
kidneys from
deceased donors function well, studies have shown that a
kidney from a living
donor, either a blood relative or an unrelated person, provides the greatest chance for long - term success.
Donated
kidneys also come from recently
deceased donors.
Analysis of the sample can determine if a
kidney donor (potential live
kidney donor or
deceased kidney donor) or a patient inherited two APOL1 gene renal - risk variants that contribute to poorer renal allograft survival after transplantation.
Freedman, Barry I., et al. «APOL1 Genotype and
Kidney Transplantation Outcomes From
Deceased African American
Donors.»
These observations support testing for APOL1 renal - risk variants in
deceased African American
kidney donors to improve the organ allocation process.
Nearly 20 percent of
kidneys that are recovered from
deceased donors in the U.S. are refused for transplant due to factors ranging from scarring in small blood vessels of the
kidney's filtering units to the organ going too long without blood or oxygen.
Furthermore, paired
kidney transplants using organs from
deceased or live
donors, makes compelling sense from a cost perspective, compared to the alternative of the pain and discomfort of
kidney dialysis treatment.
The NPRM's proposed approach did not differentiate between situations in which the
donor was competent to consent to the donation — for example, when an individual is donating blood, sperm, a
kidney, or a liver or lung lobe — and situations in which the
donor was
deceased, for example, when cadaveric organs and tissues were being donated.