On December 22, 2008, Drs. Horovitz and Chahine
issued a letter to stockholders underscoring the Board's and
management's commitment to act in the best interests of Avigen's stockholders and emphasizing the swift and
decisive actions already taken to preserve cash since the AV650 announcement.
More critically, we submit that the doubling of GC judges is an unnecessary distraction from less visible and arguably more
decisive issues such as case
management and productivity per personnel unit.