Not exact matches
Indeed, the apparent
decline in Trump's spontaneous speech — that is, the unscripted answers he gives in interviews and press conferences — was one
of the first behaviors that spurred debate about whether he was suffering
cognitive decline or mild
cognitive impairment.
A small 2009 study found that
of the 41 participants with mild
cognitive impairment, those who had higher stress ratings also had faster rates
of cognitive decline.
Ongoing studies at Uppsala University in Sweden have shown that the chemical agent dubbed Pittsburgh Compound - B, or PIB, is a highly accurate marker
of plaque buildup and that its abundance in the brain can predict whether patients with mild
cognitive impairment will develop Alzheimer's — and when that
decline will likely start.
People with mild
cognitive impairment were defined as those who have a slight
decline in cognition, mainly in memory in terms
of remembering sequences or organization, and who score lower on tests such as the California Verbal Learning Test, which requires participants to recall a list
of related words, such as a shopping list.
[Bryan James et al., «Life Space and Risk
of Alzheimer Disease, Mild
Cognitive Impairment, and
Cognitive Decline in Old Age»]
«It was the quality
of sleep that predicted future
cognitive decline in this study, not the quantity,» said lead author Terri Blackwell, MA, senior statistician at the California Pacific Medical Center Research Institute (CPMCRI) in San Francisco, Calif. «With the rate
of cognitive impairment increasing and the high prevalence
of sleep problems in the elderly, it is important to determine prospective associations with sleep and
cognitive decline.»
«Results from this study, and the growing literature suggesting that OSA,
cognitive decline and AD are related, may mean that age tips the known consequences
of OSA from sleepiness, cardiovascular, and metabolic dysfunction to brain
impairment,» Dr. Osorio said.
Conversely, those with negative scans experienced much less
decline: 90 percent
of participants with mild
cognitive impairment but no plaque did not progress to Alzheimer's.
Brain imaging using radioactive dye can detect early evidence
of Alzheimer's disease that may predict future
cognitive decline among adults with mild or no
cognitive impairment, according to a 36 - month follow - up study led by Duke Medicine.
Other research studies have reported a
decline in social networks in people with Alzheimer's disease and Mild
Cognitive Impairment (MCI), and previous literature has shown psychological well - being in older age to be associated with reduced risk
of developing Alzheimer's dementia.
Basak's laboratory, which is focused on
cognitive interventions to improve abilities that
decline with age, is conducting further research to evaluate differences among various types
of video games, long - term effects
of cognitive training using the games, and effects on patients already experiencing mild
cognitive impairment.
Compared with men with sodium levels
of 141 - 142 mmol / L, men with levels
of 126 - 140 mmol / L were 30 % more likely to have
cognitive impairment at baseline and 37 % more likely to experience
cognitive decline over time.
«We are delighted to announce the award
of Recovery Act funds to many dedicated, hardworking scientists committed to advancing scientific discovery into Alzheimer's disease and
cognitive impairment,» said NIA Director Richard J. Hodes, M.D. «Over the next two years, the recipients will use this unprecedented boost in research funds to help reach our ultimate goal
of understanding age - related
cognitive decline and reducing the individual and societal burden
of this devastating disease.»
Methods: From the Amsterdam Dementia Cohort, we included 429 non-demented elderly with subjective
cognitive decline (SCD; n = 206, 61 ± 9 years, Mini-Mental State Exam (MMSE) 28 ± 2) and mild
cognitive impairment (MCI; n = 223, 67 ± 8 years, MMSE 27 ± 2), with a... mean follow - up
of 2.5 ± 1.6 years.
The operationalization
of mild
cognitive impairment (MCI) led to targeting earlier symptomatic cases
of the illness and treatment strategies based less on pathology and more on a chance to halt or slow
decline than there would be earlier in the disease.1 With the development
of amyloid imaging, MCI due to AD diagnosis was refined, 2 and early - stage AD was extended further to include preclinical AD, 3 wherein a positive amyloid positron emission tomography (PET) scan or diagnostic low levels
of cerebrospinal fluid β - amyloid (Aβ) indicated the presence
of pathology in people who were cognitively normal.
Interestingly, the first complaints
of memory
decline occurred on an average
of six years before mild
cognitive impairment (a condition that sometimes, but not always, progresses to dementia) was diagnosed, and about nine years before dementia was diagnosed.
«This is the first study
of its kind designed to test the effects
of a diet on the
decline of cognitive abilities among a large group
of individuals 65 to 84 years old who currently do not have
cognitive impairment,» says Martha Clare Morris, ScD, a nutritional epidemiologist at Rush and principal investigator
of the study.
Researchers from the Wake Forest School
of Medicine found that aerobic exercise appears to boost thinking skills and brain volume in adults diagnosed with mild
cognitive impairment, a condition that sits in between normal age - related memory
decline and more serious dementia.
His group has developed a new approach to the treatment
of Alzheimer's disease, and this approach has led to the discovery
of subtypes
of Alzheimer's disease, followed by the first description
of reversal
of symptoms in patients with mild
cognitive impairment and early Alzheimer's disease, with the ReCODE (Reversal of Cognitive Decline)
cognitive impairment and early Alzheimer's disease, with the ReCODE (Reversal
of Cognitive Decline)
Cognitive Decline) protocol.
The ingredients in this formula have been clinically proven to improve symptoms
of Subjective
Cognitive Decline (SCD), Mild
Cognitive Impairment (MCI), and Early Alzheimer's Disease.
Cognitive impairment leads to a
decline in quality
of life and is often the first sign
of the most insidious form
of dementia, Alzheimer's disease.
The age - related
decline in growth hormone and associated IGF - 1 has been linked to age - related muscle atrophy, increased adipose tissue, and neuronal dysfunction.2, 9 In fact, growth hormone replacement therapy in elderly men has been shown to increase lean body mass.9 Growth hormone therapy (1 mg / day — for 5 months) has also been used to improve
cognitive function in healthy adults and adults with mild
cognitive impairment.10 While only modest amounts
of growth hormone cross the blood - brain barrier, IGF - 1, which is actually responsible for the
cognitive benefits, gets across just fine.
Certain types
of mental
decline result from exposure to toxins and to both endogenous and exogenous oxidizing agents — all
of which appear to contribute to brain inflammation, scarring and
cognitive impairment.
Besides, it can contribute to memory
impairment, lower the risk
of cognitive decline and help boost overall immunity.
A 2010 meta - analysis which included nine studies which looked at the effects
of coffee / caffeine on different measures
of cognitive impairment and / or
decline (four studies on Alzheimer's disease; two on dementia or
cognitive impairment; three on
cognitive decline), found a reduced risk
of cognitive decline across different measures
of cognitive impairment (mean risk ratio 0.84) with caffeine intake, with moderate heterogeneity14.
As HGH levels were increased in otherwise healthy adults and those who were in the beginning stages
of mild
cognitive impairment and Alzheimer's disease, treatment began to ameliorate their
cognitive declines as measured by numerous tests described in the Neurobiology
of Aging in 2006.
The group was free
of severe
cognitive and physical
impairments, the researchers said, though some were experiencing
declines in their hearing or vision.
The longitudinal study involving 957 Chinese seniors aged 55 years or older has found that regular consumption
of tea lowers the risk
of cognitive decline in the elderly by 50 per cent, while APOE e4 gene carriers who are genetically at risk
of developing Alzheimer's disease may experience a reduction in
cognitive impairment risk by as much as 86 per cent.
My client could only remember three
of the 10 items and was
declined for coverage due to what was thought to be a
cognitive impairment.»
The researchers analyzed information from 100 patients who likely have Alzheimer's disease, 60 patients with mild
cognitive impairment, 100 with subjective
cognitive decline, and a control group
of 26 healthy individuals.
People with mild
cognitive impairment that improves in the shorter term remain at increased risk
of future
cognitive decline