Sentences with phrase «decrease in the zinc»

The Bongará Zinc Mine Project was in production from 2007 to 2008, but was closed due to the global financial crisis and concurrent decrease in the zinc price.

Decreases in zinc concentrations, including in rice and wheat, could plunge an additional 150 million to 200 million people into zinc deficiency, the researchers calculate.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Zinc production, meanwhile, decreased by 7 % year - on - year to 242 700 t for the first quarter, mainly as a result of the disposal of the Rosh Pinah mine, in Namibia, and the Perkoa mine, in Burkina Faso, to Canadian miner Trevali Mining in August last year.

For example, children with zinc deficiency also have decreased growth, rashes (acrodermatitis enteropathica), and poor wound healing, etc., in addition to an impaired immune system.

And concentrations of phytate, which can interfere with zinc uptake, decreased only in wheat.

The drug also appeared to reduce the amount of the protein amyloid beta (which forms toxic plaques in the brains of Alzheimer's patients) by decreasing the levels of metals such as zinc and copper.

The body maintains a precise balance by increasing or decreasing the amount absorbed in the gut and by active mechanisms that take place inside cells after zinc is digested.

For example, supplementing your diet with zinc for as little as six weeks has been shown to cause a significant improvement in testosterone among men with low levels, while restricting dietary sources of zinc has been found to lead to noticeable decreases.

You want to decrease phytic acid in foods you consume as much as possible because it impairs the absorption of a number of minerals, including zinc, calcium, and iron (although it's to be noted that the impairment only happens during that meal, not at subsequent meals).

Alcohol also decreases zinc levels in the body.

Without adequate amounts of zinc, the testicular cells lose the ability to convert lipids, concentration of androgen receptors decrease and levels of aromatase in the liver are inhibited.

Meats will help ensure adequate intake of iron, zinc, and protein with the decrease in breast milk and formula.17

Prasad AS, Beck FW, Bao B, et al: Zinc Supplementation Decreases Incidence of Infections in the Elderly: Effect of Zinc on Generation of Cytokines and Oxidative Stress.

In regards to acne, zinc is especially helpful working as an anti-inflammatory agent, helping in prevention of breakouts but also decreasing scarrinIn regards to acne, zinc is especially helpful working as an anti-inflammatory agent, helping in prevention of breakouts but also decreasing scarrinin prevention of breakouts but also decreasing scarring.

On the flip side, numerous studies show that a zinc deficiency will result in a dramatic decrease of testosterone levels.Experts agree that diet is better than sup - plementation when it comes to zinc.

Research supports this association finding that when you lower zinc intake in healthy men that levels of testosterone decrease as well (26).

Beyond that, there are numerous nutritional supplements that could be effective based on their biochemical functions: • Chromium picolinate: Chromium is required for proper function of the insulin receptor, and has been proven to aid in glucoregulation and insulin sensitivity.58, 59 • Zinc: Insulin degrading enzyme requires zinc as a cofactor.57 • High - quality cod liver oil: To balance the n - 6 / n - 3 ratio and decrease inflammatZinc: Insulin degrading enzyme requires zinc as a cofactor.57 • High - quality cod liver oil: To balance the n - 6 / n - 3 ratio and decrease inflammatzinc as a cofactor.57 • High - quality cod liver oil: To balance the n - 6 / n - 3 ratio and decrease inflammation.

Those who took spirulina paired with zinc had a 47 percent decrease of arsenic in the body.

Also, using zinc supplements for greater than 14 days can cause a decrease in other essential minerals in the body, causing additional concerns, notes «The Merck Manual Home Health Handbook.»

We know that zinc is useful for constraining the immune system, we know that vitamin A decreases sebum production but with vitamin B5 we are in the dark.

In 1997 Ochi et al5 demonstrated that patients with Tinnitus had significantly decreased zinc levels and that supplementation with doses of 34 - 68 mg of zinc for more than 2 weeks significantly improved their tinnitus.

In a recent study done in the Journal on Nutrition, scientists discovered that low levels of some vitamins and minerals including zinc were associated with a decreased metabolic rate — and therefore less calorie burninIn a recent study done in the Journal on Nutrition, scientists discovered that low levels of some vitamins and minerals including zinc were associated with a decreased metabolic rate — and therefore less calorie burninin the Journal on Nutrition, scientists discovered that low levels of some vitamins and minerals including zinc were associated with a decreased metabolic rate — and therefore less calorie burning.

The growing fetus in the body has a high demand for zinc and lactation can also decrease zinc storage in the body.

It appears that a zinc deficiency may result in decreased neurologic functioning, activity, which therefore would interfere with cognitive function.

The studies that found zinc to be ineffective may have used a dose of zinc that was too low or have had taste - enhancing compounds known to decrease the effectiveness of zinc, such as citric acid (found in citrus fruit), tartaric acid, sorbitol, or mannitol.

The association between zinc deficiency and decreased survival in HIV - 1 — infected individuals indicates the need to carefully consider therapeutic options.

Oral zinc supplementation in Down's syndrome subjects decreased infections and normalized some humoral and cellular immune parameters.

However, adding zinc to nutritional supplementation for underweight, full - term infants in developing countries seems to decrease the risk of death.

Animal studies show that excessive dietary intake of calcium decreases zinc absorption, however, studies have not been done in humans.

Although plant sources contain zinc, they are also high in phytic acid, which binds to zinc, forms an insoluble compound and decreases its bioavailability.

Absorption decreased in the presence of calcium, zinc, iron, and phytate; the copper in copper oxide is in a form that can not be readily used by the body

Serum concentrations of zinc and copper are decreased in dogs with experimental pancreatic insufficiency, whereas serum iron and transferrin saturation are increased.

Supplementation may be beneficial in dogs with long - term decreased liver function as these dogs often have low liver zinc levels.

Elevated atmospheric CO2 is associated with decreased plant nitrogen concentration, and therefore decreased protein, in many crops, such as barley, sorghum, and soy.210, 211,212,213 The nutrient content of crops is also projected to decline if soil nitrogen levels are suboptimal, with reduced levels of nutrients such as calcium, iron, zinc, vitamins, and sugars, although this effect is alleviated if sufficient nitrogen is supplied.214 Fourth, farmers are expected to need to use more herbicides and pesticides because of increased growth of pests215, 216,217,218 and weeds219, 220 as well as decreased effectiveness221 and duration222of some of these chemicals (Ch.

Altered agricultural conditions, including extreme heat, expanded water demands, and increased severe weather events, will affect food availability and cost, particularly in vulnerable regions in which child undernutrition is already a major threat.43 The decreased protein, iron, and zinc content of certain major crops has been demonstrated for plants grown under increased CO2 conditions, 44,45 carrying significant implications for child nutrition.