Sentences with phrase «decreased reward sensitivity»

So both increased and decreased reward sensitivity could lead to obesity?

Not exact matches

This, along with preclinical studies showing that D3 receptor antagonists interfere with drug seeking and cue - and stress - induced reinstatement (68), suggest that up - regulated D3 receptor signaling in midbrain might contribute to drug craving and to decreased sensitivity to reward in marijuana abusers (see below).

Positive emotionality was inversely associated with MP - induced increases in midbrain DA, which could reflect the fact that in midbrain, D2 and D3 are autoreceptors; therefore, their stimulation would result in decreased DA release in striatum (including accumbens)(74), leading to decreased sensitivity to reward and amotivation (75).

The externalizing pathway highlights the underlying neurological systems of increased reward sensitivity and reactivity combined with decreased effortful control and regulation that are imbalanced and competing during adolescence (i.e., dual systems model), which further contributes to adolescence being a high - risk period for the onset of substance use and comorbid behavior problems [80, 81].