Sentences with phrase «decreasing cholesterol synthesis»
Animal studies suggest that green tea extracts may help lower plasma cholesterol by decreasing cholesterol synthesis and hampering the liver's production of LDL.
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Additionally, the Joslin work showed a connection between the decrease in brain cholesterol synthesis and appetite.
They found decreased expression for almost all of the genes of cholesterol synthesis, including a gene called SREBP - 2, which acts as a master regulator for cholesterol production.
The problem is, that since we've shown that cholesterol doesn't necessarily cause heart disease, and that cholesterol is necessary for cell regeneration, hormone synthesis and many other important jobs in the body, decreasing the body's ability to produce cholesterol might be (and is) the wrong approach!
Despite this possibility, mevinolin, the active ingredient in red yeast rice, is capable of reducing 7 - dehydrocholesterol levels, 22 and simvistatin (Zocor) not only inhibits the synthesis of mevalonate but also enhances the conversion of 7 - dehydrocholesterol to cholesterol by increasing the expression of 7 - DHCR.23 Simvistatin thereby hits the pool of 7 - dehydrocholesterol with a double - whammy, both decreasing its synthesis and increasing its degradation.
In the case of heart disease, recent research has shown that pear fibers are able to bind together with bile acids in the intestine, lowering the pool of bile acids and decreasing the synthesis of cholesterol.
Viscous fibers may interfere with the absorption and enterohepatic recirculation of bile acids and cholesterol in the intestine, forcing the liver to synthesize more cholesterol to meet the need for bile acid synthesis, and thus decreasing circulating cholesterol.