Sentences with phrase «decreasing the ability for»

For rare cell populations, these losses in recovery and viability present challenges for end users performing research on a process with potential for transfer to clinical scale by decreasing the ability for process time and cost efficiency.

«They show that microplastic [tiny plastic] debris decrease the ability for a fish to hatch from its egg.»

«It can also reduce your options and can make dating more difficult, because you're narrowing your field of opportunities and decreasing the ability for the laws of average to work for you.»

D - mannose is a simple sugar that works in a similar way to cranberries by also decreasing the ability for bacteria to adhere to the bladder wall.

This legislation also decreases the ability for those in the sex trade to screen their clients prior to meeting, which increases the risk of violence.

Not exact matches

I expect, however, that there will be three first - order effects that will be very similar to those that followed the BP spill: 1) increased public consciousness of the dangers inherent in transporting oil and oil products and more aversion to having these products moved nearby; 2) increased calls for alternatives to oil rather than alternative means of transporting oil; and 3) decreased trust in regulators» and firms» abilities to sufficiently mitigate risks from transporting oil.

Beyond that the adrenal gland responsible for secreting the stress response hormone becomes fatigued, resulting in decreased immunity to infection, reduced ability to repair the body and increased inflammation and tissue damage.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

services does not decrease over time as we expect, or we are not able to establish VSOE for professional services revenue, then our ability to achieve profitability will be negatively impacted.

For in - house recruiters, the ability to share applicant information with the relevant hiring manager, as well as schedule interviews and gather feedback from those same hiring managers within one system can save time and decrease the number of days in the hiring cycle.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

JED has been described as «an ecumenical sharing of abilities and expertise» and a partnership which makes «good, economic sense in these days of decreasing financial resources for the work of the church.»

The ability to provide consistent product, reliable supply and regular and transparent assurance that Australian food products are safe not only allows market access in these regions, but also enables the charging of premium prices and decreases the potential for non-tariff barriers.

Children that don't get the nutrients their bodies need will often have decreased cognitive abilities and performance in the classroom.These children are also at a higher risk for disease, which means they will miss classes.

If we wish to impact and decrease infant mortality in our state, then the ability to provide human milk for all babies in need is crucial,» said Harley Ginsberg, MD, Section Head of Neonatology and Medical Director of Neonatal Intensive Care at Ochsner Baptist.

Because of its snug comfort, The Ollie Swaddle will help decrease irritability and fussiness and increase the ability for baby to self soothe and calm themselves down to fall back asleep.

The previous fall, an ad campaign sponsored by the American Society for Reproductive Medicine (ASRM) had warned, «Advancing age decreases your ability to have children.»

«Introducing solid foods early means that the baby gets less breast milk over the course of their infancy, and that decreases the ability to get optimal benefits, like protection against infection,» said Dr. Alice Kuo, from the UCLA Center for Healthier Children, Families and Communities.

The approach halts further necrosis and can save a baby's life, but it often leaves infants with insufficient intestine and puts them at risk for long - term complications, such as short bowel syndrome, which requires feeding support for life due to the intestines» decreased ability to absorb enough nutrients.

The aforementioned Parents article noted that lack of sleep decreases people's ability to think clearly, which is especially dangerous for new parents.

In a press release, Pratt said the company's initial goals are to decrease the likelihood of car accidents, make driving accessible to everyone «regardless of ability,» and bring extra mobility to the home — «particularly for the support of seniors.»

Many good government groups had the expectation that the workgroup's proposals would help empower individual members while decreasing the speaker's ability to control all legislation, something they saw as playing into the charges against Silver, who had long resisted calls for basic technological changes to increase transparency.

Researchers from the University of Michigan, Wayne State University and Friedrich Miescher Institute for Biomedical Research in Switzerland found that suppressing the animal's ability to taste its food - regardless of how much it actually eats — can significantly increase or decrease its length of life and potentially promote healthy aging.

Studies document decreased reaction times, worsened managerial skills, less ability to concentrate, and an increased risk for injury even when alcohol can no longer be detected in the blood... all of which add up to major economic consequences.

Quickly switching between websites may reflect anhedonia (a decreased ability to experience emotions), as people desperately seek for emotional stimulation.

Guessing that the reduced ability to control force in patients with PD was related to decreased dopamine — which makes it harder to «recruit» neurons for a particular task — the researchers devised a brain stimulation experiment to further test their hypothesis.

While we tend to have an equal ability to detect touch and pain, scientists found that our acuity for simple touch decreases towards the center of the body.

By testing athletes with highly developed stereo acuity, researchers determined that repetitive training decreased their processing time, and that this ability was persistent for six months after the training ended.

The previous fall, an ad campaign sponsored by the American Society for Reproductive Medicine (ASRM) had warned, «Advancing age decreases your ability to have children.»

These promised to provide a new therapeutic target for treating obesity, with the researchers finding that they share the fat - burning abilities of brown cells, though they do decrease in number as we approach middle age.

They are also commonly referred to as «repair cells» for their ability to heal injured organs or body parts by accelerating tissue repair and regeneration, decreasing inflammation as well as increasing blood flow through the growth of new blood vessels.

Your fat tissue contains the most abundant source of mesenchymal stem cells (MSCs) in your body — a class of repair cells which have the ability to decrease inflammation, repair or replace damaged tissue while stimulating new blood vessel growth for improved blood flow.

IL - 6 alters the ability of the liver to respond to caloric deprivation by preventing the liver from generating available sources of energy that compensate for decreased caloric intake.

This innovative treatment utilizes adult stem cells (from your body fat) which have the ability to decrease inflammation, repair damaged tissue, facilitate better cell - to - cell communication and stimulate new blood vessel growth for better blood flow to the affected area (s).

Nutritional deficiencies impair lung growth, favour infections and decrease the ability of cells to control inflammatory processes, for example through a lack of anti-oxidative factors.

A mutation in BRCA1 / BRCA2 genes decreases the body's ability to suppress breast tumors, thereby increasing the risk for breast cancer.

This experimental molecule is being investigated for its ability to decrease the transcription of lipogenic genes in cells.

While it's true that a tall lifter should go for the sumo - style, this position can also be less powerful because the greater distance between the feet and the rest of the body leads decreases the lifter's ability to generate force.

Ironically, at the same time as your ability to absorb some nutrients decreases, your need for them increases.

«If you learn to breathe less than normal, your desire for food decreases and your ability to live off small amounts of food increases.»

Researchers have found that it takes only 4 days of insufficient sleep for your body's ability to process insulin (the hormone in charge of transforming sugar, starches and other types of food into energy) to drastically decrease.

Our ability to positively reframe a situation can act like a mechanism for increasing gratitude and decreasing depressive symptoms.

Accredited practising dietitian and spokesperson for the Dietitian's Association of Australia, Sonya Stanley, says in her experience picky eaters tend to avoid fruit and vegetables — or eat a very limited range — which decreases their ability to achieve a balanced and healthy diet.

I often use the various IF protocols in my clinic for their powerful ability to decrease inflammation, increase cellular repair, and to heal the gut.

The problem is, that since we've shown that cholesterol doesn't necessarily cause heart disease, and that cholesterol is necessary for cell regeneration, hormone synthesis and many other important jobs in the body, decreasing the body's ability to produce cholesterol might be (and is) the wrong approach!

Many keto enthusiasts praise the diet for its anti-inflammatory effects on the GI system and ability to increase energy levels and muscle mass while decreasing hunger pangs and total caloric intake.

The unified ability you gain with Non-Dominant Side Training ™ decreases wasted effort and strain from overcompensating with your dominant side for the deficiencies and inefficiencies of an untrained non-dominant side.

Ginger is famous for its beneficial effect on our digestive system and its ability to decrease nausea.

«If we're consuming carbohydrates at a faster rate than our bodies are utilizing them for energy, that extra glucose gets stored in the fat cells of the liver, which decreases its ability to break down excess estrogen and allowing it to hang around in our systems longer than it should.

But doing this right is often overlooked, and is one of the biggest causes of extended illness, extended recovery time (for injuries) and a real decrease in your ability to come back 100 %.