Sentences with phrase «decreasing your risk over»

Rebalancing also does not automatically decrease your investment risk, but again, depending on market conditions, it may slightly increase or slightly decrease your risk over shorter periods of time.

Not exact matches

Because spreading your money across different investments decreases your risk, increases your upside returns over time and does not cost you anything.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

As always, more return leads to more risk but by spreading out your portfolio over a number of different assets you can continue to decrease your risk of holding only one type of investment.

These risks have decreased somewhat over the past three months.

They use a conventional glide path, which gradually decreases the allocation to equities with age to a constant after retirement, to determine target risk levels over the life cycle.

The only thing is that you have to cool the broth over might so you can skim off the fat content to decrease the risk of botulism.

Finally, we have reviewed a large - scale study on high blood pressure showing an association between high levels of protein intake (in the vicinity of 100 grams per day) and significantly decreased risk of high blood pressure over an 11 - year period of time.

This slower oxidation increases the wine's freshness and decreases the risk of buyer's remorse over shitty, faulty wine.

That this House: (1) notes with concern the impact on the Dairy Industry of the Coles milk pricing strategy and that: (a) dairy farmers around the country are today seriously questioning their future having suffered through one of the worst decades in memory including droughts, floods, price cuts and rising cost of inputs such as energy and feed; (b) unsustainable retail milk prices will, over time, compel processors to renegotiate contracts with dairy farmers and the prospect that these contracts will be below the cost of production may force many to leave the industry; (c) the fact that supermarkets are now selling milk cheaper than many varieties of bottled water will be the straw that finally breaks the camel's back for many dairy farmers; and (d) the risk of other potential impacts includes: (i) decreased competition as name brands are forced from the shelves; and (ii) the possible loss of fresh milk supplies to some parts of the country as local fresh milk industries become unviable; and (2) calls on the Government to: (a) ask the ACCC to immediately examine the big supermarkets and milk wholesalers after recent price cuts to ensure they do not have too much market power and are not anti-competitive in their behaviour; and (b) support the new Senate inquiry into the ongoing milk price war between the country's major supermarket chains».

The proportion of people aged 18 years and over who consumed more than two standard drinks per day on average, exceeding the National Health and Medical Research Council lifetime risk guidelines, decreased to 19.5 % in 2011 - 12 from 20.9 % in 2007 - 08.

Our GEL - Kayano ® 24 model offers overpronators stability and comfort, to improve running efficiency and decrease risk of injury over varying distances.

As a result, prevention and treatment approaches that decrease relapse risk and / or increase the intervals between major depressive episodes over the long term hold the greatest promise to benefit mothers and children.

Babies who can roll themselves over are at a significantly decreased risk of SIDS, which experts believe is because babies with that ability have also developed the maturity to sense trouble during sleep and move into a safer position.

It allows for easier breastfeeding, better sleep for parents and infants, reassurance that your baby is right there for you to watch over and protect, and possibly even decreases the risk of SIDS.

«Restricting calories can slow your basal metabolism, and if by - products of metabolism accelerate aging processes, calorie restriction sustained over several years may help to decrease risk for chronic disease and prolong life,» says lead author Leanne M. Redman, associate professor of Clinical Sciences at Pennington Biomedical Research in Baton Rouge, LA.

«Albany absolutely can not hand regulatory control over ridesharing — a proven way to decrease the risk of drunk driving — to TLC controlled by tax and limo interests in New York's most populous counties,» he wrote.

Of all four groups studied, only those at high genetic risk for Alzheimer's who did not exercise experienced a decrease in hippocampal volume (3 %) over the 18 - month period.

In 2012 in Lancet, a CTT meta - analysis of 27 randomized trials found that even among people with no previous vascular disease, those who had a 39 - point decrease in LDL had a 9 percent lower overall mortality risk over about five years.

However, results for women who decreased their alcohol intake over the five year period were not significantly associated with risk of breast cancer or coronary heart disease.

Fear over potential cancer and other risks has fueled a dramatic decrease in the number of women using hormone replacement therapy over the past 15 years.

Declines in VA acuity over time were associated with increased mortality risk in part because of decreasing levels of IADL over time.

The runners» risk for breast cancer mortality decreased over 40 % per MET hour per day.

Dubbed the «Age of Obesity and Inactivity» by the Journal of the American Medical Association, this runaway weight gain threatens to decrease average U.S. life span, reversing gains made over the past century by lowering risk factors from smoking, hypertension, and cholesterol.

Loeb points out that much of the concern over cancer risk is that, as part of standard therapy for advanced prostate cancer, tumor growth is decreased by drugs that drastically reduce rather than increase male hormones.

Although the prevalence of diabetes mellitus increased over time, other risk factors, such as cigarette smoking, measured systolic blood pressure, and total cholesterol values, decreased.

I've learned about over the years and, you know, like the doctor said, people talk about the helmet — you improve the helmet, you know, you'll decrease the risk of concussion.

The HIV - specific IgG3 response correlated with decreased infection risk, but the effect waned over time, similar to the declining efficacy observed in the RV144 trial.

They note that average health risks decreased «slightly but significantly» over the three years of the study — probably because of the health promotion programs that were available to employees.

To investigate whether individuals treated with statins experienced a decreased risk of bloodstream infection by S. aureus, researchers from the University Hospitals in Aalborg and Aarhus, Denmark and the University Hospital in Seville, Spain analyzed records of close to 30,000 people using Danish medical registries over a 12 - year period.

Although estrogen doses in oral contraceptives have decreased appreciably over the years, with pills in the 1960s typically containing more than double the estrogen dose of pills in the 1980s, the reduction in endometrial cancer risk was at least as great for women who used the pill during the 1980s as for those who used it in earlier decades.

Interestingly, an imaging study comparing DA increases using BPND and 4 - propyl -9-hydroxynaphthoxazine -LRB-[11C] PHNO)(radiotracer with > 20-fold higher affinity for D3 over D2 receptors, and presumably more sensitive to competition with endogenous DA)(63, 64) in response to a stressor in individuals at high risk for schizophrenia showed that those who abused marijuana had a blunted response, consistent with decreased DA signaling (22).

Rising levels of education among US adults over the past 25 years may also have contributed to decreased dementia risk.

The fact that the risk elevation was apparent directly after cancer diagnosis, and decreased in magnitude over time, supports the conclusion that the risk increase may be traced to the diagnosis itself rather than the emotional or physical suffering related to progression of the cancer or to its treatment.

The risk of cardiovascular related illness and death is known to decrease after smoking cessation in patients with coronary heart disease, 40 reducing dramatically over the first three years, 41 but reducing the risk of developing lung cancer after smoking cessation generally takes longer.9 41 This review has found evidence that after lung cancer has been diagnosed, reductions in risk of developing a second primary or recurrence were associated with quitting within seven years, suggesting that, even at this stage, the prognostic outlook can be improved by smoking cessation.

Research proves over and over again that people who put an emphasis on produce, fish, whole grains, and healthy fats not only weigh less, but also have a decreased risk for heart disease, depression, and dementia.

Research published in the medical journal Circulation showed that among approximately 5,000 people over a period of 15 years, those who took higher levels of magnesium had a decreased risk of metabolic syndrome.

What's more, the American Heart Association has concluded that a short walk in the park can decrease the risk of getting high blood pressure, increased cholesterol levels and can prevent the likelihood of developing diabetes if done consistently over time.

Over six years, the researchers found that increases in the amount of fat and decreases in fat density were linked with changes in the risk for heart disease.

Multiple sets properly stimulate the muscles and potentially decrease the injury risk over the long term.

A lot of guys are accustomed to turn around to talk to others while they're lifting, lifting their head up while bench pressing or looking down while curling, and these habits can lead to chronic neck and back pain over time, decreasing your back strength and increasing the risk of a serious injury.

As the concentration of sulforaphane is a lot higher in broccoli sprouts than in mature broccoli, exactly the same decrease in risk theoretically may be had with a weekly intake of slightly over an ounce of sprouts.

It surveyed 40,000 people over 16 years, showing that eggs decreased the risk of death by stroke.

What it found was that between the ages of 50 and 65, risk was increased in people who ate a protein - rich diet, whereas in people over 65 years old experienced a decrease in mortality.

This type of research, which is the gold standard when it comes to scientific validation, demonstrates that diets rich in animal products confers a metabolic advantage over the alternatives, decreasing the risk of obesity, diabetes, cardiovascular disease, and dementia, consistently out - performing high carbohydrate diets.

Sweet cherries reduce uric acid levels in the bloodstream and, in fact, increased sweet cherry intake has been associated with a 35 % decreased risk of gout attacks (over a 2 - day period with 3 servings or approx. 16 cherries / day).

Among these studies are studies on more than 19,000 children representing of 47,000 patient years of growth hormone treatment; a prospective study of 100 adult growth hormone — deficient patients followed for 1 to 4 years, a study of 910 children treated with growth hormone for 11 years, a study of 32 adults and children followed for up to 40 years treated with growth hormone (average 10.8 years); a study of 180 growth hormone — treated children followed for over 6 years with reduced cancer recurrence risk (RR 0.6); a prospective analysis of 289 growth hormone — deficient adults who, after 5 years of growth hormone therapy, showed lower risk of malignancy (RR 0.25) and decreased risk of myocardial infarction (RR 0.19) and early mortality (RR 0.22) compared with the untreated group.

Similarly, a Japanese population study of over 75 thousand men and women found a decreased risk of lung cancer among people who consumed soy products on a regular basis (Isoflavone intake and risk of lung cancer: a prospective cohort study in Japan.

Americans spend over $ 20 billion each year on statin drugs, [1] which are prescribed under the guise of decreasing your risk for heart trouble by «improving» cholesterol ratios.

Coconuts contain over 50 percent of medium chain fatty acids, which have many health benefits, including weight loss, increased energy, seizure reduction, improved digestive and cognitive health, and a decreased risk for heart disease and chronic inflammation.