Sentences with phrase «deep brain»

This method therefore provides a patient specific approach to tuning parameters that may dramatically improve efficacy of deep brain stimulation.

These are deeper brain structures, which serve as «switching stations» for information.

From these correlations, the investigators were able to create a map of connections from deep brain stimulation sites to the surface of the brain.

While receiving deep brain stimulation, rats showed a noticeable improvement in treadmill walking speed and endurance.

While deep brain stimulation may improve function compared with those who do not receive it, little evidence exists on whether the treatment has any benefits to life expectancy.

But it isn't practical for human deep brain stimulation.

A directional deep brain stimulation device for the treatment of epilepsy and other brain disorders.

In the future, more patients may benefit from deep brain stimulation, although the team is moving forward slowly with this project to be sure to pick the best subjects.

Deep brain stimulation in mice also triggers the production of proteins that encourage neurons to form new connections.

Working with colleagues from Harvard Medical School and Würzburg, researchers from Charité — Universitätsmedizin Berlin have been examining the use of deep brain stimulation in the treatment of Parkison's disease in an attempt to optimize treatment effectiveness.

His first therapeutic effort will use deep brain stimulation in the ancient neural networks he has charted to counteract depression.

Already, researchers have developed devices such as deep brain stimulators for treating Parkinson's disease, cochlear implants for restoring minimal hearing in profoundly deaf people, and a computer interface called BrainGate that allows fully paralyzed individuals to accomplish simple tasks via a robotic arm.

Her brain scan studies show decreased activation in deeper brain structures in the limbic system, which governs emotions and other physiological functions; hence the relaxed, de-stress effect from acupuncture.

Now, however, DARPA has released two calls for grant applications, with at least one more likely: The first, called SUBNETS (Systems - Based Neurotechnology for Emerging Therapies), asks researchers to develop novel, wireless devices, such as deep brain stimulators, that can cure neurological disorders including posttraumatic stress (PTS), major depression, and chronic pain.

With four patients implanted with deep brain electrodes to identify the areas of the brain where their epileptic seizures originated, Dr. Miller was able to stimulate each side of the brain while the patient read words.

Yet, as the now 52 - year - old scientist watched a neurosurgeon and his team prepare to use a technique called deep brain stimulation (DBS), a very different kind of patient was never far from his mind.

The firing of a single neuron is believed to be the basic unit of brain computation, and these studies are accomplished through the collaboration of neuroscientists and neurosurgeons, with the consent and participation of patients who undergo deep brain electrode placement for diagnostic or treatment procedures.

At the 2014 American Association of Neurological Surgeons Annual Meeting, neurosurgical researchers from University Hospitals (UH) Case Medical Center presented results from a small study looking at deep brain electrode implantation as a possible alternative to the traditional WADA test used prior to epilepsy surgery.

* In the large clinical trials on deep brain stimulation for epilepsy that have been run so far (SANTE and RNS), most participants do not see their seizures eliminated.

Anikeeva and her colleagues injected custom - made, 20 - nanometer iron oxide particles into a region of the rodents» brains called the ventral tegmental area (VTA), a well - studied deep brain structure essential to the experience of reward, which plays a central role in disorders such as addiction and depression in people.

Although optogenetics is not yet possible in humans, Dr. Paz believes we may be able to use similar therapies like deep brain stimulation to target a specific area in real time to stop a seizure.

To support their behavioral studies, the HHMI Janelia group performed deep brain imaging in freely - moving AGRP - specific calcium reporter mice using miniature head - mounted fluorescent microscopes.

A pilot study performed deep brain stimulation of the frontal lobe of Alzheimer's patients.

This level of specificity has not yet been accomplished in current deep brain stimulation therapies,» says Tonegawa.

Parkinson's disease patients treated with low - frequency deep brain stimulation show significant improvements in swallowing dysfunction and freezing of gait over typical high - frequency treatment.

Gray matter is located on the surface of the cerebral cortex and also includes deep brain structures such as the thalamus and basal ganglia.

Possibly, they receive their input from deeper brain areas that are involved in motion control,» explains Professor Remy.

That was the question researchers addressed in the study Intralaminar Thalamic Deep Brain Stimulation Ameliorates the Memory Deficit and the Dendritic Regression in β - Amyloid Infusion Rats, led by Sheng - Tzung Tsai, MD..

Professor Kwang - Soo Kim, a leading expert in Parkinson's disease, said the current golden standard of treatment is to replenish the patients» dopamine levels through medication or by using a surgical method to do deep brain stimulation using electric currents.

Parkinson's patients may be somewhat lacking in this respect and therefore eat less and lose weight, whereas the weight gain exhibited after deep brain stimulation seems to point to an increase in pleasure and motivation associated with food.

The surprising finding published today in Current Biology shows that in humans and other primates, information from the eyes is not only sent to the visual cortex for the complex processing that allows stereoscopic vision, but also could feed directly into deep brain circuits for attention and emotion.

If deep brain stimulation could dial a patient's thalamus back up, Schiff expected that it would activate the rest of the brain as well.

While it's far too early to know whether deep brain stimulation helps those with early Alzheimer's, the initial findings suggest the technique is worth further study, said lead researcher Dr. Andres Lozano.

The technique doesn't concentrate on any physical damage or deep brain activity that may be associated with tinnitus, but rather, it looks to train out errant nerve activity.

These findings could potentially make several important contributions to our understanding of how deep brain stimulation (DBS) using theta bursts can modulate episodic memory formation.

To extend the capabilities of this technology beneath the cortex, an optrode system for targeted deep brain stimulation and recording will be developed and integrated into the optical apparatus.

During a key experiment in the 1990s, for example, researchers damaged the neocortex of female hamsters after birth but spared deeper brain structures.

Lifting the head, moving the eyes, scooting around, bringing things to the mouth and all of the other amazing things your baby is learning to do helps her discover her surroundings and make deeper brain connections.

«Systems approaches to optimizing deep brain stimulation therapies in Parkinson's disease.»

«Correct connections are crucial: Individualizing deep brain stimulation in patients with Parkinson's disease.»

«We are now in the process of developing a complete procedure for connectivity - based deep brain stimulation, which will then need to undergo further validation studies.»

They're not fluctuating due to meds if they're just using the [deep brain] stimulation.»

Major technical challenges must be overcome before the approach can be tested in humans, but the technique could eventually provide a wireless, nonsurgical alternative to traditional deep brain stimulation surgery, researchers say.

To search for such cells, the Mosers and their team delved into the medial entorhinal cortex (MEC), a slim arc of deep brain tissue where they had discovered the grid cells in 2005.

Dr. Gradinaru's research interests focus on developing tools and methods for neuroscience (optogenetic actuators and sensors; tissue clearing and imaging) as well as on investigating the mechanisms underlying deep brain stimulation (DBS) and on the long - term effects of DBS on neuronal health, function, and ultimately behavior.

EEG — which only requires attaching a few wires to someone's head — can't penetrate deeper brain structures or show where a seizure begins, critical information for doctors weighing treatment options, says Olivier Baud, a developmental neuroscientist at the Robert Debré University Hospital in Paris.

«But perhaps the most exciting implication is that our tools, when paired with appropriate activity modulator genes, could enable non-invasive deep brain modulation for the treatment of neurological diseases such as Parkinson's disease.»