To support their behavioral studies, the HHMI Janelia group performed
deep brain imaging in freely - moving AGRP - specific calcium reporter mice using miniature head - mounted fluorescent microscopes.
«We were fortunate that a group of collaborators, including Fritjof Helmchen from the Brain Research Institute and David Jörg and Benjamin Simons from the University of Cambridge, joined efforts to bring together their expertise in
deep brain imaging and theoretical modeling, which allowed us to obtain and understand our data.»
Not exact matches
«Using the probe's
imaging function during experiments, our medical collaborators would be able to see
deep inside the
brain of a living organism and guide the placement of the probe to the right
brain region.»
2010 and beyond Innovative new
imaging techniques are revealing intricate microstructures
deep within the
brain.
The group performed non-invasive
brain imaging in the first 80 college - aged participants of the DNS, showing them pictures of angry or fearful faces and watching the responses of a
deep brain region called the amygdala, which helps shape our behavioral and biological responses to threat and stress.
Magnetic resonance
imaging scans pinpointed the right insular area as the culprit, a region
deep inside the
brain linked with the part of the nervous system that sets off stress - related responses.
Dr. Gradinaru's research interests focus on developing tools and methods for neuroscience (optogenetic actuators and sensors; tissue clearing and
imaging) as well as on investigating the mechanisms underlying
deep brain stimulation (DBS) and on the long - term effects of DBS on neuronal health, function, and ultimately behavior.
The microscopy techniques that permit
imaging of
brain cells in awake mice generally can't visualize anything
deeper than a fraction of a millimeter below the
brain's surface, whereas the mPOA is several millimeters
deep.
Resting - state functional magnetic resonance
imaging allows investigating whole -
brain connectivity changes during pharmacological modulation of the level of consciousness.Low - frequency spontaneous blood oxygen level - dependent fluctuations were measured in 19 healthy volunteers during wakefulness, mild sedation,
deep sedation with clinical unconsciousness, and subsequent recovery of consciousness.Propofol - induced decrease in consciousness linearly correlates with decreased corticocortical and thalamocortical connectivity in frontoparietal networks (i.e., default - and executive - control networks).