For example, by
deep sequencing bacterial DNAs from diseased and healthy subjects, the inventors propose that features associated with certain microbiome compositional and / or functional features (e.g., the amount of certain bacteria and / or bacterial sequences corresponding to certain genetic pathways) can be used to predict the presence or absence of an autoimmune condition.
Not exact matches
In this study that used
deep DNA
sequencing of
bacterial specific genes, the guts of both males and females exposed to lead had all of the similar complexity in microbiota as those not exposed.
Deep sequencing of isolates taken from a single patient carrying MRSA for the longest period revealed that although all isolates were of the same clade, there were small genetic differences between them, suggesting
bacterial diversity within a single carrier.
Specifically, 60 % of the
bacterial species of the
deep ocean detected by massive
sequencing techniques are unknown.
TFUMseq (Temporal FUnctional Metagenomics
sequencing) uses shotgun libraries cloned into a recipient
bacterial species, tracked over time in gnotobiotic mice by
deep sequencing and computational methods.
Deep sequencing of cerebral white matter - derived RNA from the HIV (n = 4) and ODC (n = 4) patients and SURG (n = 2) groups revealed bacterially - encoded 16 s RNA
sequences in all brain specimens with α - proteobacteria representing over 70 % of
bacterial sequences while the other 30 % of
bacterial classes varied widely.