Sentences with phrase «deep sequencing technology»

Highlights of Relevant Experience: Managed matrix team of U.S. and U.K. scientists in first ever large - scale use of US DNA TAP Store integrated liquid handling capabilities to support deep sequencing technology project to generate data for genetic rare variants and for potential asset realignment with project delivery of more than 12,000 samples prepared under extremely tight time lines for GlaxoSmithKline.

«Deep sequencing technology is now becoming a staple of scientific research.

Age - related variations in DNA methylation were analyzed by deep sequencing technology, which revealed distinct patterns, with gains in methylation in older individuals occurring at genomic sites that were unmethylated in young individuals, and vice versa.

Not exact matches

Frey likens Deep Genomics» technology to a Google search for genetic mutations: researchers can query a DNA sequence, and the system will identify mutations and tell them what's going to happen and and why it might cause a certain disease.

«This is a story that couldn't have happened five years ago, but with the evolution of deep sequencing, we were able to use the technology at just the right time and harness it with what we've been working on for decades,» he says.

But the benefits of this technology for discerning the circuits of the mind go much deeper, because the virus that carries the photoreceptor genes can also carry promoter sequences that express their payload only in neurons with the appropriate molecular address.

Described in the January 7th issue of Neuron, the technique uses «deep,» highly sensitive whole - genome sequencing of single neurons and a new technology that identifies inserted bits of DNA caused by retrotransposons, one of several kinds of so - called somatic mutations that can arise as the brain develops.

Here they photographed organisms from deep - water samples and used technology to sequence the genomes of these single - celled organisms.

The technique, called ultra-rapid deep sequencing, combines deep sequencing — an emerging technology that reconstructs an entire DNA sequence from a tiny snippet of DNA — with advanced computational techniques and algorithms developed in the laboratories of Chiu and his research collaborators.

A study of this scope is possible thanks to innovative techniques for in vitro selection (such as mRNA display), as well as a revolutionary technology permitting massively parallel RNA sequencing (known as deep sequencing), which provides unprecedented speed and read accuracy.

For one thing, sequencing technologies continue to develop at a breakneck pace, and, according to Willerslev, as third - generation technologies such as nanopore sequencing are applied to ancient - DNA work, researchers will be able to probe even deeper into the biological past.

Over the past decade due to the deep - sequencing technologies, we have studied the characterization of nucleic acid alterations in a wide range of cancers generating a large body of information on how cancer develops and evolves.

These individuals had already been deep sequenced with Illumina technology, both for variant calling and estimation of DNA methylation based on treatment with bisulphite.

The event, entitled «Spring Mutations: How Deep Sequencing is Changing Protein Science,» was the first in a series of jointly hosted QBI and Gladstone symposia that will focus on cutting - edge research technologies.

ChIP - Seq (ChIP followed by deep sequencing of DNA) is an extension of ChIP technology to determine the chromatin enrichment of a transcription factor on a genome - wide scale.