Here's how it works: These disorders are recessive, which means that a baby must inherit
a defective gene from each parent to have the disease.
Not everyone who inherits the gene will get the disease, but those who do so inherit
the defective gene from both parents.
In such cases, she would have received
the defective gene from both parents; specifically, an affected father and a mother who is either a carrier or is affected herself.
It is also not surprising that prcd - PRA affected dogs (who must receive
the defective gene from both parents) have been identified in Labradoodles (Labrador Retriever x Poodle crosses), Goldendoodles (Golden Retriever x Poodle crosses) and Cockapoos (Cocker Spaniel x Poodle crosses).
Even if this occurs, there is no guarantee that you will see an affected dog from such a mating, as there is only a twenty - five percent chance of inheriting
the defective gene from both parents.
Not exact matches
If you're a carrier of a
defective gene for a recessive disorder, that means you have one normal copy of the
gene from one of your
parents and one
defective copy
from the other.
A girl who inherits one
defective copy of such a
gene from her
parents has a backup on her other X chromosome.
It is found in about 1 in 2,000 people, and occurs when an individual inherits a
defective gene copy
from both
parents.
It is an autosomal recessive (AR) disorder, in which the
defective gene must be passed on
from both
parents in order to cause disease.
Because the girl inherited a
defective version of the
gene from each
parent, she had no normal copy.
A dog bred
from mixed ancestry is less likely to inherit
defective genes for the same disease
from both
parents.
The number of breeding offspring
from higher - risk
parents should be limited, so that you avoid the possibility of multiplying a
defective gene in the breeding population.
Not nearly as simple as those due to a single pair of
defective recessive
genes that some offspring inherit
from their
parents.
This means that affected dogs must carry two
defective copies of the
gene, one inherited
from each
parent.