Sentences with phrase «defective mitochondria»

To get rid of defective mitochondria the nucleus of one egg cell has to be transferred to another egg cell bearing intact mitochondria.

However, this method raises the following problem: in every nuclear transfer, a small number of defective mitochondria are transferred into the healthy egg cell.

Lipofuscin (aging pigment) accumulates which results in defective mitochondria.

Scientists at the Vetmeduni Vienna show for the first time that even a few defective mitochondria dragged along in the transfer could cause diseases.

Moreover, the inability to remove defective mitochondria from nerve cells has been linked to numerous neurodegenerative diseases, including the more common forms of Parkinson's disease and amyotrophic lateral sclerosis (ALS).

LONDON — Wellcome Trust, the United Kingdom's largest biomedical research charity, today announced more than # 4 million in support for a pioneering, and potentially controversial, IVF treatment that could prevent some forms of muscular dystrophy and other diseases caused by defective mitochondria, the energy - generating organelle in cells.

In September, researchers announced that they had demonstrated a way to replace defective mitochondria with healthy ones.

The technology involves taking defective mitochondria, the cell's powerhouses, from a mother's egg and replacing them with healthy mitochondria from another woman.

When PINK1 accumulates on the surface of defective mitochondria, it alters a molecule called ubiquitin.

«Even when they had defective mitochondria, the cells with the retrograde response and AMPK simultaneously activated during growth were able to live as long as cells with normal mitochondrial function.»

The procedure, which has worked in monkeys, would be for women who could pass on defective mitochondria — only a woman's mitochondria survive in a fertilized egg — to a child.

237/2: 45 TNS1 mutations and gastrointestinal stromal tumors and defective mitochondria in the blistery (Tns1 knockout) D. melanogaster.

The cells had defective mitochondria — cellular power stations — and depleted levels of ATP, which is their most important fuel source.