Cloning the human gene for epimerase -
deficiency galactosemia (UDP - glucose 4 epimerase; GALE) in 1995.
Not exact matches
There are only a few indications for the use of soy - based formula milk such as infants suffering from
galactosemia or rare condition characterized by hereditary
deficiency of lactase and in situations where parents prefer a vegetarian diet for their baby.
These include the infant with
galactosemia, 53,54 the infant whose mother uses illegal drugs, 55 the infant whose mother has untreated active tuberculosis, and the infant in the United States whose mother has been infected with the human immunodeficiency virus.56, 57 In countries with populations at increased risk for other infectious diseases and nutritional
deficiencies resulting in infant death, the mortality risks associated with not breastfeeding may outweigh the possible risks of acquiring human immunodeficiency virus infection.58 Although most prescribed and over-the-counter medications are safe for the breastfed infant, there are a few medications that mothers may need to take that may make it necessary to interrupt breastfeeding temporarily.
Sometimes a baby can be born with a condition called primary lactase
deficiency or with
galactosemia, in which they can't tolerate breast milk.
Sure, there are some babies who can not tolerate lactose and these babies are fairly rare - they may have congenital lactase
deficiency and
galactosemia.
Galactosemia type II (also called galactokinase
deficiency) and type III (also called galactose epimerase
deficiency) cause different patterns of signs and symptoms.
Breastfeeding is contraindicated in infants with classic
galactosemia (galactose 1 - phosphate uridyltransferase
deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).
Classic
galactosemia, or galactose 1 - phosphate uridyltransferase [GALT]
deficiency, is a contraindication for breastfeeding.
Babies with
galactosemia have a severe
deficiency of GALT and have no other option but to eliminate all forms of lactose from the diet, including breastmilk.
The American Academy of Pediatrics recommends soy formulas for parents who do not want their child to eat animal protein, and for infants with
galactosemia or congenital lactase
deficiency.
For mothers who prefer giving formula, the AAP does not recommend soy formula for preterm infants, but states that soy formula is indicated for infants with hereditary disorders that make them unable to properly digest milk, such as
galactosemia and the rare condition hereditary lactase
deficiency.