Sentences with phrase «deficient mice in the study»

Fetuses from zinc - deficient mice in the study were 38 percent smaller on average than those from the control group fed a diet with zinc included.

Not exact matches

Cadwell cautions that such a strategy must await further evidence to confirm his theory that this trend in Paneth cell death occurs in people deficient in ATG16L1 who are, like his study mice, prone to higher risk of inflammatory disease and transplant rejection.

Dr. Schwarcz and his colleagues studied mice which were deficient in kynurenine 3 - monooxygenase, or KMO, an enzyme that is crucial for determining the levels of KYNA in the brain.

The new study found that vitamin C activated TET2 function in mice engineered to be deficient in the enzyme.

In this study, Cherqui's team transplanted wildtype HSPCs into an FA mouse model, reporting that the HSPCs engrafted and soon differentiated into macrophages in key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cellIn this study, Cherqui's team transplanted wildtype HSPCs into an FA mouse model, reporting that the HSPCs engrafted and soon differentiated into macrophages in key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cellin key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cells.

The study compared intestinal wound healing in two groups of mice: 1) typical mice (wild type) found in nature and 2) mice genetically deficient in the healing factor IL - 10, specifically in macrophages, which impairs their ability to have normal wound repair.

In the new study, Ji's group put SHANK3 - deficient mice through a battery of sensory tests, finding that the animals had lower sensitivity than normal mice to heat and heat - related pain — akin to the soreness a person feels after a sunburn.

This study, titled «Enamel Hypomineralization and Structural Defects in Amelotin - deficient Mice,» is published in the OnlineFirst portion of the Journal of Dental Research: the journal for dental, oral and craniofacial research.

After his team first observed hair loss in Treg - deficient mice, Rosenblum learned that the genes associated with alopecia in previous studies are almost all related to Tregs, and treatments that boost Treg function have been shown to be an effective treatment for the disease.

Canaan and colleagues initially developed the FAT10 - deficient mouse to study the role of FAT10 in sepsis.

Two Dutch scientists working for the biotechnology company GenPharm International, based in California, received a patent for a transgenic mouse which is deficient in T cells and is used to study immune disorders.

Investigators studied bile production and lipid absorption in mice deficient in the KLF15 protein.

In the six - month study, which was published online in a recent edition of Biology of Reproduction, female mice were fed a control or a zinc - deficient diet for four to five days before ovulatioIn the six - month study, which was published online in a recent edition of Biology of Reproduction, female mice were fed a control or a zinc - deficient diet for four to five days before ovulatioin a recent edition of Biology of Reproduction, female mice were fed a control or a zinc - deficient diet for four to five days before ovulation.

In order to study the relationship between telomeres and liver damage, the researchers generated a mouse line deficient in TRF1 protein in the liver, thus leaving the telomeres in hepatic cells unprotected and compromising their functioIn order to study the relationship between telomeres and liver damage, the researchers generated a mouse line deficient in TRF1 protein in the liver, thus leaving the telomeres in hepatic cells unprotected and compromising their functioin TRF1 protein in the liver, thus leaving the telomeres in hepatic cells unprotected and compromising their functioin the liver, thus leaving the telomeres in hepatic cells unprotected and compromising their functioin hepatic cells unprotected and compromising their function.

It is essential the findings from the study in the dystrophin - deficient mice are confirmed in human DMD patients before its potential applications in these patients can be considered.

In the present study, the scientists created a genetically mutant mouse model deficient in type 1A BMP - receptor (BMPR1A), a key receptor for BMP - 7 which has been shown to be associated with obesity in human populationIn the present study, the scientists created a genetically mutant mouse model deficient in type 1A BMP - receptor (BMPR1A), a key receptor for BMP - 7 which has been shown to be associated with obesity in human populationin type 1A BMP - receptor (BMPR1A), a key receptor for BMP - 7 which has been shown to be associated with obesity in human populationin human populations.

In the Joslin study, scientists first examined gene expression in the hypothalamus of a mouse model of insulin - deficient (type 1) diabeteIn the Joslin study, scientists first examined gene expression in the hypothalamus of a mouse model of insulin - deficient (type 1) diabetein the hypothalamus of a mouse model of insulin - deficient (type 1) diabetes.

In their study «D - Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain,» the lab utilized SR deficient (SR - / --RRB- mice, which have < 15 % of normal D - serine levels, to validate and optimize a D - serine immunohistochemical methoIn their study «D - Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain,» the lab utilized SR deficient (SR - / --RRB- mice, which have < 15 % of normal D - serine levels, to validate and optimize a D - serine immunohistochemical methoin the Adult Mouse and Human Forebrain,» the lab utilized SR deficient (SR - / --RRB- mice, which have < 15 % of normal D - serine levels, to validate and optimize a D - serine immunohistochemical method.

In this study, we have performed a detailed analysis of the survival and tumor susceptibility of p21 - deficient mice.

For the study, the researchers treated part of a human artery — a few millimeters in diameter — with the siRNA - loaded nanoparticles and transplanted it into the abdominal aorta of an immune - deficient mouse inoculated with human T cells.

«Our study uncovered that alterations in the innate immune pathways could induce behaviors resembling obsessive - compulsive disorder in progranulin - deficient mouse models of FTD,» said Gan, who is also a senior investigator at Gladstone and a professor of neurology at the University of California, San Francisco.

«Deficient neuron - microglia signaling results in impaired functional brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red Blood Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks in the mouse brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect of orexin - 1 and crf - 1 antagonism on stress circuits: a fMRI study in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization of hydrophobic iron oxide nanoparticles with lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.

This study shows for the first time proteins interacting with Nbeal2 and points to the dysregulation of the canonical signaling pathway of Dock7 as a possible cause of the aberrant formation of platelets in GPS cases and Nbeal2 deficient mice.

In this study, when researchers gave mice bred to be apoliprotein - E deficient a purified diet containing either casein, the principal protein in dairy products, rice protein or soy protein, the mice given casein developed the largest atherosclerotic lesionIn this study, when researchers gave mice bred to be apoliprotein - E deficient a purified diet containing either casein, the principal protein in dairy products, rice protein or soy protein, the mice given casein developed the largest atherosclerotic lesionin dairy products, rice protein or soy protein, the mice given casein developed the largest atherosclerotic lesions.

Much of our knowledge of leptin comes from the study of two brands of lab mouse: the ob / ob mouse, deficient in genes responsible for leptin production; and the db / db mouse, deficient in the leptin receptor gene.

Zinc - deficient ASD mice study: Gender Dependent Evaluation of Autism like Behavior in Mice Exposed to Prenatal Zinc Deficimice study: Gender Dependent Evaluation of Autism like Behavior in Mice Exposed to Prenatal Zinc DeficiMice Exposed to Prenatal Zinc Deficiency

A study done in 2013, for example, found that mice deficient in fatty acids were more likely to develop atopic dermatitis.

For example, a recent study in the Journal of New England Nutrition, scientists found that when mice were craving sugar, they were actually «deficient in the nutrient Coenzyme NF Cappa 7.»

Previous studies have shown that STAT6 - deficient mice are more hyperactive and have lower levels of midbrain dopamine transporter [77] suggesting that STAT6 is involved in behavior [81].