Sentences with phrase «define cell identity»

Not exact matches

The Hippo pathway not only defines final tissue size by controlling developmental growth, but is also key to specifying stem cell identity and proliferation, to regeneration and tissue repair, as well as numerous cell fate decisions.

The identity and function of the fibroblast, a highly prevalent cell type in the heart, have remained poorly defined.

A genome - scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.

To understand why skin cells in diverse parts of the body have different characteristics - how cells know their «positional identities» - a fact that guides the diagnosis and treatment of many skin diseases, Dr. Chang and his colleagues are seeking to define in molecular terms how the expression of different genes in stromal cells determines their ability to affect the development of skin cells.

The sum of such interactions then gives rise to the molecular «signature» that defines a cell's identity and behavior.

In primary cells, we quantified multiple transcripts, with the identity and functional state of each analyzed cell defined on the basis of the expression of a separate set of transcripts or proteins.

Nanog is a critical factor required for what cell biologists call «stemness,» which is defined by two qualities: the ability of ES cells to divide or «self - renew» and their plasticity in assuming the identity of almost any cell type, which is also known as «pluripotency.»

MicroRNAs and long non-coding RNAs (lncRNAs) have the capacity to regulate gene expression programs, and their differential expression within immune cells highlights their potential in defining immune cell identity and function.