Instead, he suggests that «the size of the organization — in other words, the number of militants that are working —
defines the sequence of events.»
But in the living world, crystals, like the ones formed by cocoa butter in chocolate or ill - formed ones that cause sickle cell anemia, are made from molecules that are long and floppy and contain a lengthy well -
defined sequence of many atoms.
By deliberately introducing
defined sequences of dsRNA into living organisms, biologists can observe the physiological consequences of «silencing» virtually any gene in C. elegans, as well as other plants and animals.
The sequence of amino acids in a protein molecule is
defined my the sequence of the gene for that protein.
In addition, educators will need to
define the sequence of subskills to be acquired on the way to expertise.
And I am lucky to read blogs from people that are about to retire and
define sequence of return scenarios for me.
Structures or elements of no matter like a circle or a square plane or
a defined sequence of numbers and their ratios are parts of nature as music listeners know.
Not exact matches
[1:20] How the kindness
of a stranger changed Tony's life [3:35] Peter Diamandis talks about the origins
of X Prize [6:30] Technology helping the agricultural industry [7:00]
Sequencing genomes [8:55] Life - work integration [11:15] Finding your highest calling in life [12:00] Reframing what is «impossible» [14:00] Strategy vs. psychology [15:00] Changing your state [16:00] The science
of achievement, the art
of fulfillment [19:00] Living in a beautiful state [24:00] Thinking 10x bigger [28:00] Surrounding yourself with a «nothing is impossible» community [29:00] The news pollutes your mind [31:00] Tony's natural gifts and core beliefs [33:30] Overcoming failure and criticism [37:45]
Defining your environment [40:00] Life happens for you, not to you [42:00] Rituals and practices to up your game [46:30] Tony's priming process
See the
sequence: calculate the opportunity,
define your competitors, create a competitive matrix, perform a website content audit, identify the weaknesses
of your competitors, prioritize your opportunities.
Rather, specifically human existence is, in Whitehead's term, a «personal society,» i.e., a temporal
sequence of occasions which share, by virtue
of inheritance from the earlier to the later, a
defining characteristic that makes the man or woman in question just this individual and not some other.
Nepa, In the context
of a multiverse, there may not be a first cause since time and
sequence isn't even well
defined.
I mean just think about how many distinctly unique DNA combinations that could possibly exist, or the exact
sequence of events you have experienced in your life which have come to
define you.
7 - If we
defined growth as adding new material to our bodies, then DNA is living, because in the process
of replication it add new
sequences to its structure, but even in this case we have say it is non-living because DNA is not showing development which is the second part
of growth, and simply development is the changes in structure living things undergo as it grow and age.
Hartshorne beautifully
defines «social» as the coordinate processes
of weaving one's own life from strands taken from the lives
of others and giving one's own life as a strand to be woven into their lives.28 He also
defines «self - interest» as the sympathy the present self may feel for future members
of the same
sequence, and «altruism» as «whatever sympathy that self may feel for members
of other
sequences, human, sub-human, or superhuman.
On the basis
of the well -
defined structure
of the ritual positions in the rites, Van Gennep concluded that the formality
of rites
of passage, exemplified in their highly patterned
sequences of action, permits us to organize and understand a large body
of ethnographic data and to make significant cross-cultural generalizations.
A few Christians and nearly all atheists,
define creationism as believing the universe was created in a very short period
of time, in a precisely described
sequence of events.
Genetic identity, which has only a relatively definite meaning, involves (1) some «
defining characteristic» reappearing in each member
of a
sequence or family
of occasions; (2) direct inheritance by appreciably positive prehensions
of this character from previous members.
For the purpose
of this review, we
defined «high quality» as a trial having adequate
sequence generation, allocation concealment and an attrition rate
of less than 20 %.
People with mild cognitive impairment were
defined as those who have a slight decline in cognition, mainly in memory in terms
of remembering
sequences or organization, and who score lower on tests such as the California Verbal Learning Test, which requires participants to recall a list
of related words, such as a shopping list.
«Proteins are
sequence -
defined polymers and have a whole variety
of exquisite functions,» said materials scientist Jay Grate
of the Department
of Energy's Pacific Northwest National Laboratory.
In the first study
of human fungal skin diversity, National Institutes
of Health researchers
sequenced the DNA
of fungi at skin sites
of healthy adults to
define the normal populations across the skin and to provide a framework for investigating fungal skin conditions.
Scanning a genetic database, the researchers matched the faulty gene's
sequence to that
of a previously
defined family
of genes.
Recently, San Diego, California - based Illumina, one
of largest manufacturers
of sequencing machines, teamed up with Dana - Farber, MSKCC, and two other major U.S. cancer centers to
define the «cancer actionable genome» to help tailor cancer therapies.
Proteins are
defined by their unique
sequence of amino acid residues; this
sequence is the primary structure
of the protein.
Additional studies in which we more precisely
define the mechanisms
of resistance and growth in an individual's tumor with genomic
sequencing, and other means, will be important to maximize the ability to target all the critical pathways to achieve greater success.»
Thus, this study has implications for analysis
of human vaccine studies, as in addition to searching for
defined lineages it is worthwhile to perform functional analysis
of monoclonal antibodies that may have found new structural solutions to high affinity binding which can not be discerned from DNA
sequence alone.
With the complete
sequence of the human genome a reality, and with a growing body
of transcriptomic, proteomic, and metabolomic data sets in health and disease, we are now in a unique position in the history
of medicine to
define human disease precisely, uniquely, and unequivocally, with optimal sensitivity and specificity.
The isolation and
sequence of the gene encoding T8: a molecule
defining functional classes
of T lymphocytes.
Methods: Chen's research team achieved the controllable assembly
of sequence -
defined peptoids by manipulating their side - chain chemistry to tune molecular interactions.
In addition, EST and BAC end
sequence data and complete BAC insert
sequences of some randomly selected and community
defined BAC clones will be generated.
The ability
of Nanopore
sequencing to
define the complete exonic structure
of CACNA1C allows us to identify known and novel gene isoforms, including novel exons and multi-exonic skipping events and their expression across multiple brain regions.
The results suggest that the
sequenced genomes
define two microbial groups: one composed
of only a few taxa that are nearly always abundant in picoplanktonic communities, and the other consisting
of many microbial taxa that are rarely abundant.
«These extensions complement the MIxS suite
of metadata standards by
defining the key data elements pertinent for describing the sampling and
sequencing of single - cell genomes and genomes from metagenomes,» said GSC President and study co-author Lynn Schriml
of the Institute
of Genome Sciences at University
of Maryland School
of Medicine.
The relation denotes is
defined in IAO that allows us to assert the relationship between digital data
of a DNA
sequence and its corresponding physical biological material
sequence.
This kit contains all
of the reagents necessary to prepare custom gesicles to deliver Cas9 and a user -
defined, gene - specific guide
sequence.
«In our research project on pediatric leukemia we plan to use Gemcode to
define the exact chromosomal breakpoints
of large scale chromosomal rearrangements and repetitive
sequences that are typical for leukemic cells, but are difficult to characterize in short
sequence reads,» said Professor Ann - Christine Syvänen, who leads the Molecular Medicine group.
For each polymorphic site observed in a given horse sample, we
defined the ancestral state using the donkey
sequence data and computed a measure
of genetic load as the product
of the GERP score at each site and the number
of derived alleles carried by this individual at this site, averaged across sites for each individual.
Our results suggest that information on the state
of the host - parasite relationship in vivo can be provided by measurements
of the differential expression
of different var groups, and need only be
defined by short stretches
of sequence data.
Dr. Loftus» current research integrates the identification
of these types
of epigenetic modifications that mark the melanocyte regulatory genomic landscape with regulatory protein and transcription factor chromatin - binding domains, thus
defining groups
of non-coding DNA
sequences utilized in the control
of melanocyte gene expression.
The location, type, and orientation
of the inserted elements are identified using mate pairs that map in the vicinity
of the insertion site, aligning each unmapped arm to
sequences of a
defined set
of mobile elements.
Using a reverse - genetics system, in which specific viral
sequences are manipulated within the context
of a full - length infectious clone
of the virus, they have been
defining the roles
of particular viral components in influencing DENV and ZIKV infection in mice and human cells.
The bounds and frequency
of reversion alleles in patient 1 ′ s post-talazoparib DNA were
defined by DNA reads that included
sequence from both sides
of the deleted region.
Today for main -
sequence stars, the B - class is instead
defined by the intensity
of the He I violet spectrum, with the maximum intensity corresponding to class B2.
Her laboratory focuses on (1) the use
of next generation
sequencing to
define the microbiome and host immunologic features in patients with human diseases and (2) developing custom computational tools for the identification
of novel human commensals and pathogens in these inpatient populations, and (3) using statistical and functional biological methods to understand the complex interplay between the human microbiome and host biology.
More than half
of mammalian genes generate multiple messenger RNA isoforms that differ in their 3 ′ untranslated regions (3 ′ UTRs) and therefore in regulatory
sequences, often associated with cell proliferation and cancer; however, the mechanisms coordinating alternative 3 ′ - UTR processing for specific mRNA populations remain poorly
defined.
Together with Alfred Amambua - Ngwa and in collaboration with the Wellcome Trust Sanger Institute, he is working to characterise the diversity
of the local Plasmodium populations by genome
sequencing, and to devise suitable SNP markers for
defining the spatial and temporal spread
of malaria in The Gambia at the village level.
Future studies, including data from larger sample sizes
of wild - born and geographically well -
defined individuals, and full Y - chromosome
sequences from bonobos, gorillas and orangutans, promise to further our understanding
of population histories, male - biased behaviours, mutation processes, and the functions
of Y - chromosomal genes.
His current research focuses on chemical evolution
of sequence -
defined carriers for drugs, proteins and therapeutic nucleic acids, with a medical focus on tumor - targeted therapies.
The application
of whole - genome
sequencing has moved us on from
sequencing single genomes to
defining unravelling population structures in different niches, and at the - species, - serotype or even - genus level, and in local, national and global settings.
This
sequence liability may be
defined as a critical quality attribute and represents a risk to the development
of novel biologics and biosimilars alike.