Sentences with phrase «defining mechanisms of resistance»
Additional studies in which we more precisely define the mechanisms of resistance and growth in an individual's tumor with genomic sequencing, and other means, will be important to maximize the ability to target all the critical pathways to achieve greater success.»
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My studies of cancer genomes have led to characterization of multiple pediatric and adult tumor types, to development of methods that identify and characterize changes in genomic heterogeneity, to defining acquired resistance mechanisms to targeted therapies and to designing novel, personalized vaccines for individual patients.