Sentences with phrase «degenerating photoreceptor cells»

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Mutations in at least 60 genes are known to cause the disease, and many people are not diagnosed until after a a substantial proportion of photoreceptor cells, the eye's rods and cones, have already degenerated and died.

«We demonstrated that in the absence of Numb, photoreceptors are unable to send a molecule essential for vision to the correct compartment, which causes the cells to progressively degenerate and ultimately die,» adds Dr. Ramamurthy, who carried out the project in Dr. Cayouette's laboratory in collaboration with Christine Jolicoeur, research assistant.

«When horizontal cells are blocked from being formed — the immediate consequence of knocking out Onecut1 — the photoreceptors don't get what they need to survive, so they degenerate and die later on.»