PRA is caused by
the degeneration of the photoreceptor cells, rods and cones, which are needed for dark and day light vision, respectively.
«Many retinal diseases are manifested by
the degeneration of photoreceptor cells.»
Not exact matches
«If we could perhaps modulate these pathways and prolong survival
of photoreceptor cells, we might be able to delay any further
degeneration even when intervening at these later stages
of disease.»
«By putting in healthy
cells, we can basically stop and prevent the
degeneration of the
photoreceptors,» says Sally Temple, the co-founder and scientific director
of the Neural Stem
Cell Institute in Rensselaer, N.Y.
The condition is hereditary or age - related, and causes
degeneration of the
photoreceptors — light - sensitive
cells in the retina — leading to blindness.
Featured on the cover
of Developmental
Cell, a paper by OIST researchers revealed the mechanistic link between photoreceptor cell degeneration and defects in protein transp
Cell, a paper by OIST researchers revealed the mechanistic link between
photoreceptor cell degeneration and defects in protein transp
cell degeneration and defects in protein transport.
However, both Goldberg and Albini agreed there is no evidence that this kind
of therapy could have treated the patients» sight problems even if carried out correctly and only sparse evidence that adipose
cells can differentiate into retinal pigment epithelium or
photoreceptor cells, which play a critical role in macular
degeneration.
0 Research ArticleRETINAL DISEASES Human ESC — derived retinal epithelial
cell sheets potentiate rescue
of photoreceptor cell loss in rats with retinal
degeneration Karim Ben M'Barek 1,2,3, Walter Habeler1, 2,3, Alexandra Plancheron1, 2,3,
These retinal
cells are the type that are killed off in macular
degeneration, eventually leading to the death
of photoreceptors, and the gradual loss
of central vision.
ERG abnormalities are evident by 5 — 6 weeks
of age and
cell degeneration is present by 4 months, suggesting the mutant protein has a toxic gain
of function that severely compromises the early stage
of development
of the
photoreceptors.