Severe CTE was defined as tau clusters and several other
degenerative abnormalities affecting not only the cortex, but deeper
brain structures including the hippocampus, the amygdala, and the
brain stem.
Causes of seizures from within the
brain (structural
abnormalities of the
brain) include
brain tumors, strokes, encephalitis or meningitis, congenital
abnormalities (such as hydrocephalus), head trauma,
degenerative or storage diseases, infection and other causes.