Sentences with phrase «delay tumour growth»

Importantly, the inhibitor was able to synergise with the doxorubicin and help to delay tumour growth.

Now, a research team at Imperial College London has found that in a mouse model developing liver cancer, one immunoreceptor — attractive candidate for immunotherapies — promoted rather than delayed tumour growth.

Not exact matches

Employing a combination of cellular, biochemical and genetic experiments, we showed that (i) human and murine pericytes express functional Tie2 receptor, (ii) Tie2 - silenced pericytes have a pro-migratory phenotype, (iii) Tie2 downstream signalling in pericytes involves Calpain, Akt and FOXO3A, (iv) Ng2 - Cre - driven deletion of pericyte - expressed Tie2 delays developmental angiogenesis and vessel maturation, and (v) Tie2 deletion in pericytes results in a pro-angiogenic tumour vasculature with enhanced tumour growth.

(D) Deletion of Slc6a14 delays the development and growth of mammary tumours also in MMTV - Neu - Tg mice.