Next, in mouse studies, the scientists
deleted key genes, called Atg7 or Atg5, whose function was necessary for autophagy in regulatory T cells.
Not exact matches
Some researchers have proposed
deleting or disabling
key genes that are required for early embryonic development.
One such avenue, Wolf says, is that researchers may be able to
delete key monkey
genes — a procedure commonly done in mice whose populations are more homogeneous — and easily evaluate the effects in clones.
Wolf and his colleagues have used the CRISPR - Cas9 system in bovine embryos to
delete OCT4, a
gene that is known to play a
key role in the regulation of pluripotency in mammalian embryos.