Sentences with phrase «deleted tumor suppressor genes»

Not exact matches

Collateral lethality occurs when tumor suppressor genes are deleted, a nearly universal occurrence in cancer.

Correspondingly, a large number of genes with no direct role in tumor progression also are deleted as a result of their proximity to tumor suppressor genes.

Tumor suppressor genes are deleted in many cancers leading to tumor formation and grTumor suppressor genes are deleted in many cancers leading to tumor formation and grtumor formation and growth.

They discovered that the number of tumor suppressor genes or oncogenes in a chromosome correlated with how often the whole chromosome or part of the chromosome was deleted or duplicated in cancers.

Quite possibly, a tumor suppressor gene was deleted, or an oncogenic allele was duplicated.

However, in the deleted chromosome region, BECN1 is adjacent to BRCA1 (breast cancer 1, early onset), which is a breast cancer tumor suppressor gene frequently mutated in familial breast and ovarian cancers.