a virus that can be used to
deliver gene therapy drugs to cells.
Not exact matches
Gene therapy delivered to a specific part of the brain reverses symptoms of depression in a mouse model of the disease — potentially laying the groundwork for a new approach to treating severe cases of human depression in which
drugs are ineffective.
«What strikes me as innovative here is that you can make the foam almost instantaneously,» says Edith Mathiowitz, a chemist at Brown University in Providence, Rhode Island, who studies such foams for
delivering drug or
gene therapy.
Gene therapy might supply the correct gene, drugs might deliver a substitute molecule, tissue engineering might enable the tissue to repair itself, or a surgeon might repair the damage after a hernia has occur
Gene therapy might supply the correct
gene, drugs might deliver a substitute molecule, tissue engineering might enable the tissue to repair itself, or a surgeon might repair the damage after a hernia has occur
gene,
drugs might
deliver a substitute molecule, tissue engineering might enable the tissue to repair itself, or a surgeon might repair the damage after a hernia has occurred.
It uses a virus already approved by the Food &
Drug Administration for other genetic
therapies in the eye; it
delivers an ion channel
gene similar to one normally found in humans, unlike others that employ
genes from other species; and it can easily be reversed or adjusted by supplying new chemical photoswitches.
The pricing of
gene therapy, the authors suggest, will be determined by the manner in which it is
delivered, development and
drug production costs and the size of the treatable population.
«RNAi
therapies are a unique approach to cancer treatment as they have the potential to «turn off» the
genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi
drug can be
delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.»
A robot like this could potentially be used to infuse
drugs at targeted points in the brain, or to
deliver gene therapy vectors.