Sentences with phrase «deliver new genes»

Now, researchers have found a clever way of using these implants to deliver new genes right into the ear — a therapy that, in guinea pigs, dramatically improves hearing.

Not exact matches

Anderson and others are already exploring new gene - delivery methods, including nanoparticles, to better deliver gene - editing therapies to target tissues.

Gene therapy delivered to a specific part of the brain reverses symptoms of depression in a mouse model of the disease — potentially laying the groundwork for a new approach to treating severe cases of human depression in which drugs are ineffective.

In the new study, Duke University researchers overcame several of these obstacles by using a non-pathogenic carrier called adeno - associated virus, or AAV, to deliver the gene - editing system.

Using a new technique to deliver gene - therapy - like intervention directly where it's needed, researchers at Thomas Jefferson University successfully increased or decreased the muscle tone of the anal sphincter in appropriate animal models.

«New innovative method for delivering genes into cells: Modification of cell physiological function with novel parallelized electroporation of mammalian cells by using electrostatic manipulation in a water - in - oil droplet.»

Some newer vaccine candidates use harmless viruses such as modified adenoviruses to deliver genes that encode immunizing viral proteins.

New insights into specific gene mutations that arise in this often deadly form of brain cancer have pointed to the potential of gene therapy, but it's very difficult to effectively deliver toxic or missing genes to cancer cells in the brain.

In a step toward accelerating the production of new gene therapies, scientists report in ACS Nano that they have developed remote - controlled, needle - like nanospears capable of piercing membrane walls and delivering DNA into selected cells.

The new AAV vectors can also deliver genes that code for colorful fluorescent proteins; such proteins are useful in identifying and labeling cells.

Through colorful anecdotes and commonsense explanations, author Richard C. Francis, who holds a Ph.D. in biology, delivers an engaging tour of the new science of epigenetics, the study of environmental influences on gene expression.

It uses a virus already approved by the Food & Drug Administration for other genetic therapies in the eye; it delivers an ion channel gene similar to one normally found in humans, unlike others that employ genes from other species; and it can easily be reversed or adjusted by supplying new chemical photoswitches.

The use of next - generation gene sequencing in newborns in neonatal intensive care units (NICUs) may improve the diagnosis of rare diseases and deliver results more quickly to anxious families, according to new research in CMAJ (Canadian Medical Association Journal).

Other research at U-M is developing new options for treating brain cancer through immunotherapy — harnessing the immune system to attack cancer cells once an injection of a particular gene therapy is delivered into the brain tumor.

At a time when gene therapy has been revived as a potent form of cancer treatment, a new approach would use nanoparticles, rather than viruses, to deliver strands of DNA or RNA to tumors.

Using tiny snippets of DNA as «barcodes,» researchers have developed a new technique for rapidly screening the ability of nanoparticles to selectively deliver therapeutic genes to specific organs of the body.

In addition to his basic science programs, Jones has isolated and is isolating new resistance genes against potato late blight from wild relatives of potato, with the goal of using them to deliver market - favoured potato varieties that are protected from late blight by genes, rather than by chemistry.

«The failure rate to deliver drugs to CNS is unfortunately very high, so any new methods of drug, protein and gene delivery should be welcome,» says Inder Verma, Ph.D., a professor in the Laboratory of Genetics and senior author of the study published in the Proceedings of the National Academy of Sciences.

«The failure rate to deliver drugs to CNS is unfortunately very high, so any new methods of drug, protein and gene delivery should be welcome,» says Verma.

A new animal study involving virally - delivered gene therapies has indicated that high treatment doses might not be as safe as previous human trials have suggested

The modified virus then delivered the new genetic material inside the iPSCs, where the DNA region containing the broken gene was replaced with the sequence containing the normal gene.

Using a new selection method, Caltech researchers have evolved the protein shell of a harmless virus, AAV9, so that it can more efficiently cross the blood brain barrier and deliver genes, such as the green fluorescent protein (GFP), to cells throughout the central nervous system.

In the new study, Duke University researchers overcame several of these obstacles by using a non-pathogenic carrier called adeno - associated virus, or AAV, to deliver the gene - editing system.The paper appears on December 31, 2015 in Science.

Gene quickly begins to fall for the enigmatic Ginger, despite the fact that his goal was to deliver her up to his new friend Titty.