Sentences with phrase «delivering nucleic»

Genetic therapies, such as those made from DNA or RNA, face challenges because of the difficulty in delivering the nucleic acid to the right cells.

The spherical structure of the SNAs is the ideal architecture for delivering nucleic acids into cells for gene regulation, Mirkin said.

In a trial described in Nature Materials, the team showed they could deliver the nucleic acids DNA and siRNA into human cells in the lab, using the nanoneedles.

They can penetrate the cell, bypassing its outer membrane, to deliver nucleic acids without harming or killing the cell.

More importantly, it can deliver nucleic acids more effectively.

Not exact matches

The miR - 182 was safely delivered to the tumors using spherical nucleic acids, DNA and RNA arranged around a gold nanoparticle center.

However, in the past decade scientists realized that exosomes play important roles in many biological functions through capsuling and delivering molecular messages in the form of nucleic acids and proteins from the donor cells to affect the functions of nearby or distant cells.

They can also deliver precise doses of drugs, nucleic acids, or proteins to targeted points on the cell.

Anderson and Langer have previously developed nanoparticles, now in clinical development, that can deliver siRNA to liver cells called hepatocytes by coating the nucleic acids in fatty materials called lipidoids.

Scientists are also breaking ground with nucleic acid platforms that have the potential to deliver cancer vaccines, for neoantigens and other targets.

«These proteins have a unique ability to deliver proteins and nucleic acids inside the cell,» says Liu.