Sentences with phrase «delivering therapeutic drugs»

Berkeley Lab researchers have developed a new family of nanocarriers, called «3HM,» that meets all the size and stability requirements for effectively delivering therapeutic drugs to the brain for the treatment of a deadly form of cancer known as glioblastoma multiforme.

Not exact matches

A pharmaceutical hit compound, like those discovered by Vogel and her co-authors, is a compound that is a promising candidate for chemical modification so it can eventually be delivered to patients as a therapeutic drug.

«If nanoparticles are carrying a drug to deliver, different uptake could mean different therapeutic efficacy and other important differences, such as safety, in clinical data.»

Richard Hargreaves, executive director of imaging at Merck Research Laboratories, says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early in a drug discovery and development program by focusing the selection of doses to study on those proven to deliver enough drug to the target therapeutic sites.»

In order to achieve therapeutic levels at the pathological site, physicians need to deliver large amounts of the drug that may cause adverse effects to other organs in the body.

Unlike conventional drugs, BNPs can be designed to deliver therapeutic agents specifically to the site of inflammation.

To test the capsule's real - world applications, the team used both mathematical modeling and animal models to investigate the effects of delivering a sustained therapeutic dose of a drug called ivermectin, which is used to treat parasitic infections such as river blindness.

«If we go back 10 years and ask what is the most important parameter [to developing a therapeutic particle], people would immediately think of the particle's size and then its surface chemistry,» says University of California, Santa Barbara, chemical engineering professor Samir Mitragotri, who develops microscopic particles of different shapes and tests their ability to deliver drugs, but was not associated with DeSimone's study.

The company plans to develop and commercialize its innovative mRNA drugs — initially for rare diseases and oncology — while partnering drug candidates in other therapeutic areas in order to rapidly deliver this innovation to patients.

A DNA - covered submicroscopic bead used to deliver genes or drugs directly into cells to treat disease appears to have therapeutic...

By delivering mRNA drugs via IV to the liver, and directing liver cells to express functional proteins, Moderna can potentially stimulate production of therapeutic proteins in ways that can not be achieved with other current technologies.

Extracellular interactions are excellent therapeutic targets because they are directly accessible to systematically delivered drugs such as monoclonal antibodies.

This discovery — authored by UCSD investigators Severine Boillee, Koji Yamanaka, Cleveland and others and published in the June 2 issue of the journal Science — confirms the importance of the new therapeutic approach, which delivers an antisense drug directly to the whole nervous system, including non-neuronal cells.

Because viruses have evolved such effective methods for finding their target and utilizing the host cells» own molecular machinery, scientists are modifying viruses into long - lasting therapeutic vehicles that can deliver drugs to specific cells or tissues or selectively target and destroy tumors.

therapeutic engineering — developing and discovering drugs and advanced materials and techniques for delivering drugs to local tissues with minimized side effects

Intraocular drug devices, such as the one in this clinical study, have advantages over topical ocular drug administration (eye drops) because they deliver constant therapeutic levels of drug directly to the eye.

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Therapeutic and restorative processes, such as Koori and Murri courts, drugs courts and healing circles, are ways in which the criminal justice system can help to rebuild relationships and deliver positive outcomes for the entire community.