Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to
more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state
AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient
demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Recent movements in the exchange rate have also been reflected in indexes of trade prices; the export price index rose by
more than 16 per cent over the past year, with higher prices for base metals, chemicals, and petroleum
aided by higher world prices and increased
demand.
Demands include reduction of trade barriers,
more stable commodity prices for raw materials, easier access to foreign technologies, better terms of
aid and rapid expansion of industrialization.
and when the U.S. Congress balked at providing
more aid in 1985 he went on television to denounce the «craven submission of our leaders and Congress to the
demands of communism, [which] makes you sick to your stomach.»
You
demand band -
aids, piggy - back rides, and one
more bedtime story.
This also
aids in supporting the working or pumping mom who is able to pump a
more accurate daily volume that is equivalent to what the baby is
demanding.
Advocates rallied at Foley Square in Manhattan as part of a nationwide «Day of Action» to
demand that the U.S. government approve
more aid for the heavily damaged island.
they chanted,
demanding the state honor a settlement in the Campaign for Fiscal Equity lawsuit that requires it to provide
more aid to under - funded school districts.
ALBANY — Lawmakers for months
demanded Gov. Andrew M. Cuomo give them a bigger role in dispensing billions of dollars in economic - development
aid and also insisted on
more transparency in selecting projects for big tax breaks and grants.
«The
more we know about listening in
demanding environments, and listening effort in general, the better diagnostic tools, auditory management (including hearing
aids) and auditory training will become,» Sacchinelli said.
Try these to meet your sweet tooth's
demands: Honey — Made by nature, it has the added bonus that it is
more slowly breaks down into the bloodstream and is actually easier on the stomach and
aids digestion.
The total
demand for and resulting cost of the Pell Grant program grew exponentially between 2007 and 2011 as a result of
more Americans enrolling in college and lower family incomes during the Great Recession.58 In 2011, to compensate for an inadequate reserve to fund the growing
demand of Pell Grants, Congress cut year - round Pell Grant eligibility, which was restored this year, and eliminated graduate student subsidized loans.59 This affected the student
aid packages of students nationwide.60 By cutting the Pell Grant reserve, President Trump and Secretary DeVos risk the ability to fund future upticks in Pell Grant
demand, thereby requiring either future reductions to eligibility, lower awards, or cuts to other education programs.
Progress on
more demanding trails is
aided by the All Terrain driving mode.
While the
demand continues to grow for
more financial
aid, the question is whether
more organizations will rise to the challenge and fill the gap.
The Legal
Aid, helped by lawyer Scott Torguson, is appealing to the Fair Debt Collection Practices Act to assert that the charges
demanded are
more than necessary.
But this paper doesn't do that, it looks
more like an attempt to blame African drought on «global warming», presumably laying the foundation for
demands for
aid from Europe and the US.
But it meant Democrats and a
more - spineless - than - ever Obama caving in to conservative
demands that we gut important social programs that lend
aid to the nation's poor and middle class in a time of economic difficulty.
Substituting in natural gas, wind, and solar for coal is a (relatively) manageable task, and the transition is
aided by the fact that 1) renewables keep getting cheaper, 2) new technologies and policies are facilitating
more flexible grids, and 3) electricity
demand in the United States has stagnated for years, thanks to improvements in energy efficiency.
Traditional thinking has been to attempt to increase the supply to deal with the
demand:
more lawyers,
more money for legal
aid,
more clinics,
more judges,
more courts, etc..
There is «unprecedented
demand» for legal
aid from... [
more]
But LAO miscalculated
demand for legal services and gave out
more legal
aid certificates than they could afford.
There is «unprecedented
demand» for legal
aid from refugees and immigrants, and LAO isn't getting enough
more money to deal with that
demand.
(para 119) ``... We agree that remuneration solely on the basis of time spent on a case is a disincentive to dealing with cases efficiently...» (para 120) However, fairness in remuneration
demands that the rate for dealing with a legal
aid case... should ideally be based on objective criteria that adequately capture the complexity of cases and allow a
more accurate determination of the likely work which a provider has to invest in a case in order to deal with it appropriately.»
In the case of access to the judicial system by low - income individuals, numerous studies show there is always
more of a
demand for services than legal
aid programs can provide.
Where, perhaps, government in the past has been too blinkered, has been by trying simply to squeeze
more from the system for the same cost (or less, when factoring in the lack of inflationary increases) rather than addressing whether services are procured in the right way and properly understanding the drivers for rising costs (the latter when their own research has shown that government is itself a driver through legislation, the growing number of offences and the associated
demand for legal
aid).
The device comes with Apple's dual - core, 1.4 GHz A8 processor,
aided by a quad - core PowerVR GX6450 graphic processor (which is actually the successor of the same GPU from iPhone 5s, but has been adjusted for the new,
more demanding resolution.)
And some studies have suggested that low - income students do better when they start their academic careers at
more demanding colleges and universities — schools that also offer
more in financial
aid.