Sentences with phrase «demonstrate efficacy of this model»

Not exact matches

To demonstrate the chip's efficacy in modeling disease, the team doped different regions of the brain with the drug Phencyclidine hydrochloride — commonly known as PCP — which simulates schizophrenia.

NeuroPhage has accumulated extensive preclinical data on this candidate, demonstrating its efficacy across disease models of Alzheimer's and Parkinson's disease, tauopathies and other related diseases characterized by aggregation of amyloid beta, tau, and alpha - synuclein proteins.

Indeed selected compounds demonstrated efficacy in several animal models of CNS related disorders such as depression, obesity, addiction, and psychosis.

There are currently no disease - modifying treatments that have been shown to slow the progression or delay the onset of HD in humans; however, several compounds have demonstrated promise in animal models of HD.1 Robust and sensitive markers of disease progression are required to assess their efficacy in humans.

Green's work to implement a flipped classroom model throughout an entire school — and be able to demonstrate that it resulted in improved test scores and college readiness — paved the way for a nationwide discussion about the efficacy of the current classroom structure.

For bipolar disorder, a number of models are in development, including MoodSwings (http://www.moodswings.net.au).46 It is expected that, if formal trials demonstrate efficacy, these programs will become widely used due to their cost - effectiveness, convenience and reach.