Sentences with phrase «demonstrated changing factor»

Stop basing models on caloric theory and regional assumptions I'm ecology which entails weather and not climate, or climate without a demonstrated changing factor like GHG's.

Not exact matches

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sfactors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sfactors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sFactors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

This standardization was the product of many factors, including: (1) professional politics within the mental health community, (2) increased gov involvement in mental health research and policymaking, (3) mounting pressure on psysts from health insurers to demonstrate the effectiveness of their practices,,,, Alan Stone, president of the APA in 1976, concluded that social psy and social activism, «carrying psyc on a mission to change the world, had brought the profession to the edge of extinction» (Wilson, 1993, p. 402)

Scientific research increasingly demonstrates that large - scale intensive meat production uses disproportionate amounts of land, water, and feed, adds markedly to climate change and is a factor in water pollution and food contamination.

«The studies demonstrating advantages of breastfeeding for infants and mothers suggest that many of the benefits are directly related to the duration of breastfeeding, The composition of human milk does not change markedly from 12 to 24 months, including most nutrients and bioactive factors.

A prior study by this group, which was also conducted in concurrence with the Beijing Olympics, demonstrated that pollutions levels were linked to physiological changes that increase risk for cardiovascular disease, and that these same air pollution reductions resulted in improvements in several risk factors

While previous studies had examined the impact of climate change - induced weather patterns on violence and the increased danger of violence in weak or failing states, this is the first study to demonstrate that the combination of the two risk factors is even more dangerous than they would be separately.

«For the first time, we were able to demonstrate, in surgically resected metastases, that treatment with bevacizumab in combination with chemotherapy before metastasectomy also changes the clinical significance of the growth factors as potential biomarkers,» explains Stefan Stremitzer, one of the lead investigators from MedUni Vienna's Department of Surgery.

Several trials have demonstrated that the cardiomyocytes of rodents maintained on IER become more resilient to ischaemic injury induced by occlusion of the left coronary artery 18, 21, 29, which translated into improved long - term survival following such injury in one study.21 In addition, within these studies, associations have been found between the cardiovascular improvements and markers of oxidative stress 24, 30, inflammatory responses 18, 24, 29, 30 and increases in circulating levels of adiponectin.29 Collectively, these reported changes in biochemical and physiological cardiovascular risk factors would be expected to suppress atherosclerotic development and preserve cardiovascular health.

I believe that nutrition has some influence on the disease course, but as MS is a multifactoral illness (genetic AND SEVERAL environmental factors), it is too naive to think one could completley stop it only by dietary changes, as real life experience demonstrates.

Confirming this are RCTs which demonstrate that low - carb diets which are high in MUFAs and PUFAs and relatively low in saturated fat result in favourable changes in cardiovascular risk factors, including weight loss.

He and his co-authors recommend that dating sites change the algorithms to match on factors demonstrated by research to be more effective at predicting long - term compatibility.

The push to change teacher evaluations has been driven largely by nonprofit groups and politicians, and it follows research demonstrating that teacher effectiveness is the most important in school - factor affecting student performance.

All it demonstrates is that there is more than one causal factor, as is well known, with aerosols (from fossil fuels and volcanoes), land - use changes (through affecting CH$ and CO2 levels and albedo) and solar irradiance all playing a role.

Last but not least, this scenario demonstrates how, in the usual case, CO2 concentration lags, but is a major factor in, the temperature changes.

Thank you for agreeing that there are other factors at work in global warming and bearing in mind the strength of those as demonstrated by climate history then any claim that man - made factors are anywhere near as large as 100 % or greater are going to have to demonstrate the current and past natural changes and how they interact.

For example, Seth Borenstein's AP story gave a quote demonstrating a rule about climate change stories: omitted factors can only make the effect of warming worse, never less.

History, however, demonstrates that changes of this scale and significance result not from a single cause, but rather from a confluence of factors.»

This manual demonstrates, through contributions from leading authors, how environmental risk factors such as pollution, chemical contamination and climate change will bring diseases and death.

AFTER the fact, we hear explanations, but if we don't have enough information to see decadal changes coming, how can we be certain the rapid rise from ~ 1980 - 2000 wasn't at least 50 % due to a combination of decadal factors (due to the uncertainty in our models, as demonstrated by failure to predict the slowdown)?

Comparison of empirical evidence with proxy - based reconstructions demonstrates that natural factors appear to explain relatively well the major surface temperature changes of the past millennium through the 19th century (including hemispheric means and some spatial patterns).

Besides demonstrating his firm grasp of the power of these various factors to change temperatures, this remarkable matching of theory to real - world data also tells us just how ornery the climate beast may be: the orbital changes that paced the ice ages were incredibly small.

In Virginia, a court may consider any of the following factors, among others, in making a decision: The age and physical and mental condition of the child, giving due consideration to the child's changing developmental needs; the age and physical and mental condition of each parent; the relationship existing between each parent and each child, giving due consideration to the positive involvement with the child's life, the ability to accurately assess and meet the emotional, intellectual and physical needs of the child; the needs of the child, giving due consideration to other important relationships of the child, including but not limited to siblings, peers and extended family members; the role that each parent has played and will play in the future, in the upbringing and care of the child; the propensity of each parent to actively support the child's contact and relationship with the other parent, including whether a parent has unreasonably denied the other parent access to or visitation with the child; the relative willingness and demonstrated ability of each parent to maintain a close and continuing relationship with the child, and the ability of each parent to cooperate in and resolve disputes regarding matters affecting the child; the reasonable preference of the child, if the court deems the child to be of reasonable intelligence, understanding, age and experience to express such a preference; any history of family abuse; and such other factors as the court deems necessary and proper to the determination.

A person entitled to object to the intended relocation of the child may rebut the presumption by demonstrating that the detrimental effect of the relocation outweighs the benefit of the change to the child and the relocating person, based upon the following factors.

Outcome research provides us with the opportunity to argue eloquently for the worth of quality Child and Youth Care practice, in that the factors which are the cornerstone of our work (the relationships we establish with our young clients and the experiences we facilitate) are the very factors demonstrated to be therapeutically efficacious in bringing about change.

Implementation intentions have been demonstrated to be an effective tool of behavioural change in numerous settings and behaviours, displaying medium to strong effect sizes.98 — 100 Coping plans refer to plans that specify a critical barrier to the intended / planned behaviour and a specific strategy on how to cope with this barrier.101 A recent systematic review attests that the combination of action planning and coping planning seems to be most effective for behavioural change.102 Self - efficacy has also been shown to be a crucial factor in health behaviour change across different behaviours and different populations.

He and his co-authors recommend that dating sites change the algorithms to match on factors demonstrated by research to be more effective at predicting long - term compatibility.

Controlled trials demonstrate that parenting programmes can be effective in reducing childhood behavioural problems, but much less is known about the processes of change or contextual factors that influence trial outcomes.

The current review aimed to clarify the changes in identified risk and protective factors in relation to child age to identify periods in which families require an increase in support and periods in which families appear to demonstrate greater adaptation to raising children with ASD.