Four of the mAbs, 2T5C9, 2G9C, T1F11, and TB2H7,
demonstrated diagnostic potential in enzyme - linked immunosorbent assays (ELISA) by their low to sub-nanomolar cross-reactivity with recombinant wild - type (WT) and mutant TTR aggregates and lack of binding to native TTR or amyloid fibrils formed by other peptides or proteins.
Not exact matches
Bioelectronic implants, as prostheses or
diagnostic devices, have already
demonstrated their
potential to improve the lives of patients.
Gata5 a
potential diagnostic marker for congenital heart disease The finding also suggests that gata5 could be a
potential new
diagnostic marker for congenital heart defects, as the researchers
demonstrated that gata5 regulates the expression of a gene known as nkx2.5 which, when mutated in humans, causes human congenital heart defects and disease.