Sentences with phrase «dendritic cell subsets»
Calabro et al.: Differential Intrasplenic Migration of Dendritic Cell Subsets Tailors Adaptive Immunity.
https://www.jax.org/ Not exact matches
Ralph Steinman and Nina Bhardwaj, independently with other laboratories, discover the plasmacytoid dendritic cell (pDC) subset in circulating blood.
However, it is also possible to induce such responses using protein antigens, if there is a signal that promotes cross-presentation and targeting to specific dendritic cell (DC) subsets with the capacity to cross-present antigens.
Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature.
A subset of dendritic cells (DCs) that was named «plasmacytoid» because their appearance under the microscope is similar to that of plasmablasts.
Together with the more studied regulatory T cells (Tr1 and CD25 + FOXP3 + Treg), growing evidence indicates that different subsets of dendritic cells (DC), play a critical role in promoting immune tolerance.
Expression of C - type lectin, SIGNR3, on subsets of dendritic cells, macrophages, and monocytes.
She and her colleagues study the cellular and molecular aspects of the innate and adaptive immune responses (the two arms of the immune system), and more specifically, dendritic cells, a specialized subset of leukocytes that coordinate them.
The CD4 subset is capable of directing B cell responses and humoral immunity, and can modulate the actions of many other cell types including CD8 T cells, dendritic cells, macrophages, eosinophils, and basophils.
«We noticed that tumors with elevated beta - catenin lacked a subset of dendritic cells known as CD103 +,» said co-author Stefani Spranger, PhD, post-doctoral fellow in the University of Chicago's Department of Pathology.
In this effort, Dr. Zuniga made a major «hit» while a postdoctoral fellow at the Scripps Research Institute, when she initiated study into plasmacytoid dendritic cells, a subset of leukocytes that produce large quantities of the antiviral mediators type I interferons, and have significant developmental potential.
The adenosine A ₂ ₐ receptor is the main adenosine receptor expressed on immune cell subsets including T - cells, NK cells and dendritic cells and binding of adenosine to the A ₂ ₐ receptor on immune cells blocks the activation and effector functions of anti-tumor immune cells and promotes a regulatory, immune - suppressive phenotype.
These cells, along with dendritic cells, recognize the incoming undigested food particles, toxic agents, and bacterial components as foreign invaders, and present them to cells of the adaptive immune system called T and B lymphocytes, leading to clonal expansion (proliferation or multiplication of specific subsets of T and B cells) and recruitment of more pro-inflammatory immune cells to the gut through a process called leukocyte homing.