Sentences with phrase «dendritic cells in the immune system»

Two different types of dendritic cells in the immune system present antigen in different ways to elicit distinct immune responses.

Not exact matches

When the dendritic cells are activated, they train T cells — their allies in the adaptive arm of the immune system — to attack cancer cells anywhere in the body, whether at the site of the original tumor or distant metastases.

Dendritic cells are intelligence - gathering immune cells, gathering information on viruses, bacteria, cancer and fungi to aid the immune system in fighting disease.

«Suppressing a progenitor from creating the subtype of dendritic cells implicated in causing lupus, for example, could be an efficient way of treating autoimmune diseases while minimising the impact on the rest of the immune system.

One advantage of this method is that it only activates a certain type of immune cell, the dendritic cell or T - cell, and only in one part of the body, near the draining lymph nodes or tumor, which helps cut down on the system - wide side effects often seen with chemotherapy.

The study included 124 newly diagnosed patients at 25 clinical trial sites in the U.S. Two - thirds of the patients were treated with ICT - 107, an experimental vaccine based on immune system cells called dendritic cells that were exposed to six synthetic proteins, or antigens, known to be involved in GBM development.

Because the antigens were the only possible source of TB exposure, Dr. Srivastava says, antigen transfer from infected dendritic cells had to be the avenue for their absorption by other immune system cells in the lymph nodes.

In a report to be published in the journal Cell Host & Microbe online June 11, researchers showed that immune - system - triggering TB proteins, or antigens, were able to prompt a larger, prolonged immune system response just by being transported from infected dendritic cells to uninfected oneIn a report to be published in the journal Cell Host & Microbe online June 11, researchers showed that immune - system - triggering TB proteins, or antigens, were able to prompt a larger, prolonged immune system response just by being transported from infected dendritic cells to uninfected onein the journal Cell Host & Microbe online June 11, researchers showed that immune - system - triggering TB proteins, or antigens, were able to prompt a larger, prolonged immune system response just by being transported from infected dendritic cells to uninfected ones.

A microscope image shows many of the immune system's dendritic cells that were collected from a 3 - D scaffold three days after in vivo injection.

TIM - 3 is known to play a critical role in regulating the immune system, suggesting that it may be possible to target TIM - 3 on dendritic cells in order to activate T cells.

If the dendritic cells are in an environment with microbes or tissue inflammation, they tell the T cells to start an immune system attack.

Duke scientist are learning more about the process in which melanoma cells hijack dendritic cells, allowing cancer to avoid detection by the immune system.

When a dendritic cell comes in contact with an antigen that it deems foreign, it carries it to the lymph nodes, where it instructs the rest of the immune system to attack anything in the body displaying that antigen.

In vitro experiments indicated that the antihistamines work by suppressing the accumulation and function of dendritic cells, which take up peanut protein and present it to T cells of the immune system.

• The key component of this research is dendritic cells, which serve as the gate - keepers of the immune system and are present in tissues in contact with the external environment, such as the skin and the inner lining of the nose, lungs, stomach and intestines.

In 1972, while studying human immune system responses, Dr. Steinman and his mentor, the late Dr. Zanvil Cohn, discovered and named dendritic cells.

Topics covered will include how the immune system and commensal microbes interact in the context of health and disease; how dendritic cells respond to infectious or inflammatory stimuli and the roles they play in the induction and polarization of adaptive immune responses against pathogens; how the innate immune pathways regulate inflammation at mucosal barrier tissue sites and how the macrophages are involved in intestinal inflammation.

He and the Vereide Group grow precursors of human arterial cells, build colonies of dendritic cells (cells which can alert the rest of the immune system to the presence of a tumor), and use chick embryos to study the formation of early tissue layers for a possible future in which complex tissues, or even organs, can be grown to replace diseased, wounded, or malfunctioning ones.

Analyzing patterns of gene expression in individual human immune system cells, the researchers refined the definitions of the types known as dendritic cells and monocytes and identified a novel type that had been overlooked.

Dendritic cell vaccines — focus on cells in the immune system that recognize cancerous cells.

APS (also known as astragalus polysaccharide) has been shown to activate the immune system by enhancing the transformation of T lymphocytes (a sub-type of white blood cells, crucial in the regulation of immune responses), as well as the activation of B lymphocytes (which produce antibodies that are used to attack invading bacteria, viruses, and toxins) and dendritic cells, which trigger immune reactions to toxins.

Inflammatory conditions created by cells of the innate immune system, including natural killer and dendritic cells, appear to promote metastasis in inflammatory breast cancer.