Sentences with phrase «dengue infection in humans»

Not exact matches

Unlike other human antibodies under investigation that recognize both Zika and the closely related dengue virus, the antibodies used in this study exclusively target Zika, demonstrating a high specificity that could be important in avoiding potential side effects — such as enhanced dengue infection in regions where both viruses are endemic.

It notes some of the critical scientific questions regarding Zika that deserve further exploration, including: whether certain viral mutations occurred to facilitate its geographical spread; if different species of Aedes mosquitoes are capable of transmitting Zika and what that may mean for future transmission; what is apparently unique to Zika compared to other more well - known flaviviruses, such as dengue, that can explain why it can cause congenital infections, neurological conditions and encephalitis, transmit sexually and persist for long periods of time in multiple parts of the human body; and whether preexisting immunity to other related flaviviruses may impact Zika exposure and infection.

The first human trials will be done in the US in October with people at low risk of subsequent Zika or dengue infection, says Michael.

Dr. Anuja Mathew is the newest members of the iCubed team, joining the Institute in August 2015 to research human immune responses to dengue virus infections alongside world renowned Dr. Alan Rothman.

Recent studies have identified genetic variants that account for variability in human susceptibility and severity of infection and might be useful for vaccine and treatment development in malaria [80][84] and dengue [85], [86], for example.

Working with Dr. Weiskopf, we established a model of human dengue disease using HLA transgenic mouse strains, and characterized human dengue - specific CD8 + and CD4 + T - cell responses in natural infection as well as following vaccination.

After her post-doctoral fellowship, her primary research focus remained WNV and extended to dengue virus (DENV) infection in humans.

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