This will include robotic DNA extraction, genome - wide mapping with high
density gene chips (querying 175,000 DNA markers), and next - gen sequencing of the entire genome of an affected dog (interrogating every letter of the 2.4 billion letter genetic code).
In cancer, a state marked by increased protein translation and biomass expansion, HSF1 is activated and binds to numerous
genes throughout the genome, as seen in the heat map of HSF1
ChIP - Seq read
density in M0 - 91acute myeloid leukemia cells (DMSO, far left).