Sentences with word «deoxycytidine»

Radu and Nathanson and their colleagues found that an important nucleotide called deoxycytidine triphosphate (dCTP) is produced by two pathways, the de novo pathway (DNP) and the nucleoside salvage pathway (NSP).

The authors also found that a novel small molecule inhibitor of the salvage pathway enzyme deoxycytidine kinase blocked leukemia growth in mice in combination with thymidine (to inhibit the de novo pathway).

DNA methylation inhibitor 5 - Aza - 2» - deoxycytidine induces reversible genome - wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

Simultaneous quantitative determination of 5 - aza - 2 ′ - deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure - response measures of nucleoside analog DNA methyltransferase inhibitors.

Prostratin is more effective when used with both HDAC inhibitors and with 5 - aza - 2 «deoxycytidine.

They also identified a drug, 5 - aza - 2 «deoxycytidine, that inhibited this restriction process and caused HIV to reactivate and replicate.

Indeed, this point has been demonstrated by studies with DNMT inhibitors, DAC (also known as 5 - aza - 2 ′ - deoxycytidine) and zebularine.

In this study, the researchers found that the drug 5 - aza - 2 «deoxycytidine (aza - CdR) can inhibit HIV methylation and cause the virus to reactivate.