Sentences with phrase «dependence on animal models»
Not exact matches
«After the neurobiological studies pointed out the important role of the GABAB receptor in nicotine reward, and we had positive data in a variety of animal models of nicotine dependence, it was time to focus our efforts on discovery of new molecules that could become therapeutics to assist people to quit smoking.»
http://www.scripps.edu/
Subsequently, work in the Markou laboratory showed that these compounds had desirable effects on nicotine dependence in animal models, while offering a better side - effect profile than other alternatives under study (full agonists at the same receptors).