Sentences with phrase «dependent allelic»
Junji Hirota at Tokyo Tech and team focused on discovering a long - range enhancer for a large gene cluster, finding an evolutionary conserved sequence motif in mammalian evolution, and elucidating enhancer - dependent allelic preference or exclusion mechanism for odor - detecting receptor genes.
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The research, conducted by Ivan P. Gorlov, PhD, Olga Y. Gorlova, PhD, and Christopher I. Amos, PhD of the newly formed Department of Biomedical Data Science, was shared in «Allelic Spectra of Risk SNPs Are Different for Environment / Lifestyle Dependent versus Independent Diseases,» and published in PLOS Genetics.
Human diseases with the largest public burden are E / LS dependent diseases, and the team found that allelic distributions for them follow that for an average human SNP which is neutral.
Secondly, highlighting the potential relevance of current findings to all diploid organisms including humans was the observation that in one compound heterozygous animal, the Xpd allelic relationship could shift from Adominant arecessive to Arecessive adominant with respect to different phenotypes in a time - dependent and tissue - specific manner (see below and Table 2).