Furthermore, the drug induced a dose - and time -
dependent apoptotic response in chemoresistant melanoma cells via inactivation of Bcl - 2 [21].
Dr. Steven R. Goodman, Editor - in - Chief of Experimental Biology and Medicine, said «This study by Huanbiao Mo and colleagues at the Texas Woman's University and UT Southwestern Medical Center demonstrates that geranylgeraniol causes dose
dependent apoptotic death of human prostate carcinoma cells.
Not exact matches
Impaired phagocytosis of
apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN - γ in a nitric oxide -
dependent manner.
TNF - α Inhibits Macrophage Clearance of
Apoptotic Cells via Cytosolic Phospholipase A2 and Oxidant -
Dependent Mechanisms.
Inhibition of Rac GTPase triggers a c - Jun - and Bim -
dependent mitochondrial
apoptotic cascade in cerebellar granule neurons.
Wing primordia subjected to CIN are characterised by tumor - like overgrowths, metastatic behavior and malignancy to the host upon blockade of the
apoptotic machinery, and this tumorigenic response relies mainly on the production of highly aneuploid cells that delaminate from the epithelium and activate a JNK -
dependent transcriptional response.