Sentences with phrase «dependent apoptotic response»
Furthermore, the drug induced a dose - and time - dependent apoptotic response in chemoresistant melanoma cells via inactivation of Bcl - 2 [21].
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Wing primordia subjected to CIN are characterised by tumor - like overgrowths, metastatic behavior and malignancy to the host upon blockade of the apoptotic machinery, and this tumorigenic response relies mainly on the production of highly aneuploid cells that delaminate from the epithelium and activate a JNK - dependent transcriptional response.