Sentences with phrase «dependent endocytic»

However, we have recently discovered that, depending on the concentration of ligand, the EGFR may also be internalised via an alternative clathrin - independent / lipid raft - dependent endocytic route: non-clathrin endocytosis (NCE)(4).

Cholera toxin toxicity does not require functional Arf6 - and dynamin - dependent endocytic pathways.

Not exact matches

In vivo dynamics of clathrin and its adaptor - dependent recruitment to the actin - based endocytic machinery in yeast.

Thus, our study shows that membrane exchange between the early endocytic and the biosynthetic / secretory pathways involves specific components of the Rab and SNARE machinery, and suggests that retrograde transport between early / recycling endosomes and the endoplasmic reticulum is critically dependent on the sequential action of two members of the Rab6 subfamily.

Cell surface receptors can be endocytosed by both clathrin - dependent and clathrin - independent mechanisms, but, as yet, there is no clear understanding of why alternative endocytic routes exist or how receptors are committed to a particular route.