Sentences with phrase «dependent gene regulation»

Whole genome expression data of livers of wildtype and PPARα − / − mice fasted for 24 h served as positive control for PPARα - dependent gene regulation.

Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1 - dependent gene regulation and IFN --LCB- gamma -RCB-- mediated host defenses

These modifications of p53 are believed to fine tune p53 - dependent gene regulation and cell fate decisions by affecting p53 protein stability, DNA binding affinity and interactions between p53 and other transcription cofactors.

The regulatory system to control redox balance involves sugar - dependent gene regulation and protein phosphorylation.

Not exact matches

Furthermore, if transcriptional regulation of adipose tissue function contributes to adiposity - dependent modulation of insulin sensitivity, blood pressure, and other medically important traits, then the genes that correlate with body mass will be candidates for mediating these responses and warrant further evaluation.

He received his doctoral degree in 1996 at the Ludwig Maximilians University in Munich for work on activity - dependent regulation of neurotrophin gene expression.

Benedikt received his doctoral degree in 1996 at the Ludwig Maximilians University, Munich for work on activity - dependent regulation of neurotrophin gene expression.

Thus, clock genes may mediate the leptin - dependent sympathetic regulation of bone formation.

Additionally, we identified p21waf1 / cip1, a cyclin - dependent kinase inhibitor, as a target gene of DDX3, and the up - regulation of p21waf1 / cip1 expression accounted for the colony - suppressing activity of DDX3.

To identify key molecular mediators of the ABL kinases implicated in the regulation of the ABL1 / ABL2 - dependent pathways, we analyzed the expression of individual genes for transcripts altered by loss of the ABL kinases.

Li, Y.; Reddy, M. A.; Miao, F.; Shanmugam, N.; Yee, J. - K.; Hawkins, D.; Ren, B.; Natarajan, R. Role of the Histone H3 Lysine 4 Methyltransferase, SET7 / 9, in the Regulation of NF --LCB- kappa -RCB- B - dependent Inflammatory Genes: RELEVANCE TO DIABETES AND INFLAMMATION.

This modification is of special interest to p53 - dependent anti-senescence and pro-longevity functions because genetically engineered mice with p53 serine18 mutated to alanine (p53S18A) show increased ROS levels, metabolic stress, tumor frequency, premature aging symptoms and defects in regulation of a subset of p53 target genes that include sestrins.

According to the findings it seems that regulation of gene activity is dependent on stuctural changes in the cell chromatine.