Sentences with phrase «dependent luciferase expression»

In contrast, the ability of both CoPP and HPP - 4382 to induce HMOX1 E2 ARE - dependent luciferase expression in the presence of the mutant Bach1 protein was sharply inhibited.

Expression of HMOX1 E2 - dependent luciferase expression was determined in HepG2 cells co-transfected with an HMOX1 E2 - dependent reporter plasmid and a plasmid expressing FLAG - tagged wildtype Bach1 (Figure 6A).

Nonetheless, CDDO - Me and HPP - 1014 still were able to activate HMOX1 E2 - dependent luciferase expression in the presence of mutant Bach1 proteins, indicating that the CP motifs in Bach1 are not critical for efficient derepression of Bach1 by an electrophile (Figure 6D).

Not exact matches

All three compounds were able to induce luciferase expression, demonstrating their ability to overcome Bach1 repression of HMOX E2 - dependent transcription (Figure 6C).

Luciferase expression was markedly lower in cells expressing Bach1, indicating effective repression of HMOX1 E2 - dependent transcription by Bach1 (Figure 6B).