The phrase
"depressed patients" refers to people who are feeling very sad and down for a long time, and may need help and treatment to feel better.
Full definition
Objective: To describe a group
of depressed patients that participated in a clinical intervention to improve depression treatment in rural areas.
The study provides evidence base for including preventive child mental health interventions in the treatment protocols for
adult depressed patients.
Summary: (To include comparison groups, outcomes, measures, notable limitations) This study examined the associations between treatment, social problem solving, and depression in a randomized clinical trial testing the efficacy of psychotherapy augmentation for chronically
depressed patients who failed to fully respond to an initial trial of pharmacotherapy.
In 2005 she showed that direct modulation of specific brain circuits could help
severely depressed patients who had not responded to other treatments.
In separate studies conducted by Dew et al. [9] and Lynn Chung et al. [17]
among depressed patients in Taiwan using the WHOQOL - BREF, intensity of depressive symptoms and social isolation were reported to have the greatest direct effect on all four QOL domains
SECOND OPINION Even if the drugs are effective, you would expect these results because the majority of
depressed patients do not get better on the first antidepressant they are prescribed, say numerous critics including members of the pharmaceutical industry and physicians.
Perhaps of all these positive effects on the well - being of a human patient, the most dramatic is that of a dog or a cat in the non - communicative
clinically depressed patient whose withdrawal can be gently alleviated by the introduction of the pet.
In a sample of treatment
resistant depressed patients with normal magnesium levels, those with high normal magnesium levels had a more robust response to antidepressants [29].
A 2002 study showed that it had no more effect
on depressed patients than a sugar pill (Journal of the American Medical Association).
In fact, the overall difference between medication and placebo was so small that it was «clinically insignificant» for all but the
most depressed patients, Kirsch says, a point that was consistent with his past findings.
A new study published in the Journal of the American Medical Association
found depressed patients with chronic kidney disease did not benefit from a common antidepressant.
However, our study shows there is a lot more work to do to understand why
many depressed patients do not begin treatment.»
The authors concluded that the findings of this study suggested that daily left pre-frontal rTMS produced statistically significant and clinically meaningful anti-depressant therapeutic effects for
unipolar depressed patients who are refractory to or intolerant of medications.
Stories like Williams's are familiar to Sharon Charles Haznedar, an administrative director for behavioral health services at New York's Saint Vincent Catholic Medical Centers and a psychiatric nurse practitioner, who says depression is insidious because it often renders victims unable to ask for help: «I've had
depressed patients tell me that they need a plan just to walk across the room,» she says.
In the current study with a sample of chronically depressed men and women, rates of physical and psychological victimization were similar to rates reported in a number of general community samples during a similar time period (Jose and O'Leary 2009; Schafer et al. 1998) and to rates reported with a sample of unipolar and
bipolar depressed patients (Dienemann et al. 2000).
Interpersonal psychotherapy, CBT and EMDR therapy can be effective treatments for
depressed patients as can antidepressant use, light therapy, vitamin D and supplements.
This is consistent with evidence supporting efficacy of several specific psychotherapies for moderate depression31 with less benefit for mild depression.32 Yet only a minority (30.5 %) of
depressed patients receiving psychotherapy had serious psychological distress.
«This is of importance as it suggests that it is useful to create phenotypically more homogenous groups of
depressed patients when searching for genes associated with MDD,» said co-first author Dr. Judith Verduijn.
p11 is increased in rodent brains by antidepressants or electroconvulsive therapy, but decreased in an animal model of depression and in brain tissue
from depressed patients.
• A 2006 trial aiming to treat depression with various drugs found that two out of three
depressed patients ultimately received a drug that helped put their illness in remission.
A total of 63
currently depressed patients, diagnosed with either major depressive disorder or bipolar disorder, participated in the study and were randomized to receive a single 20 - minute treatment of real LFMS or sham LFMS, where the device was on but the electromagnetic fields were inactive.
Clinical features of major depressive disorder (MDD) may help identify specific subgroups of
depressed patients based on associations with genetic risk for major psychiatric disorders, reports a study in Biological Psychiatry.
In addition, transplanting the microbiota of
depressed patients into mice can replicate the pathology in the animals.
They suggest that the frequent questioning of these drugs in media is unjustified and may
make depressed patients refrain from effective treatment.
In a study led by psychiatrist Ian Reid of Aberdeen, Schwarzbauer and colleagues performed functional magnetic resonance imaging (fMRI) scans of nine
depressed patients before and after ECT.
«Our findings are the first results in
living depressed patients to suggest that this microglial activation is most prominent in those with suicidal thinking,» said Dr. Talbot.
When he applied TMS to 14
depressed patients while they were in an fMRI scanner, he was able to confirm that subcortical areas such as the anterior cingulate — undoubtedly involved in depression — were activated as well.
Traditional therapeutic approaches often
encourage depressed patients to participate in enjoyable situations, yet the new findings suggest that some people may first need to practice allowing themselves to feel any pleasant emotions at all.
ECT, given to
depressed patients under anesthesia and after taking a muscle relaxer, sends electrical pulses to the brain through electrodes applied to the head.
In closing, I think it would be worthwhile to conduct large - scale studies of carefully
characterized depressed patients and healthy controls, using gold - standard clinical and infectious disease - related study protocols, as have already been developed for bacteria [68, 69] and viruses [70 — 76].
The rapid antidepressant response after ketamine administration in treatment - resistant
depressed patients suggests a possible new approach for treating mood disorders compared to the weeks or months
Ketamine can reduce suicidal thoughts in
depressed patients within hours of administration, a new study from Columbia Psychiatry has found.
In one early «90s study involving
elderly depressed patients, a type of folate known as 5 - methyltetrahydrofolate (5 - MTHF) was found to be roughly as effective as the antidepressant trazodone.