(c) Proof of principle experiment with pacCer - labeled cytosolic extract using biotin
for derivatization.
The process involving liquid chromatography - electrospray ionization - tandem mass spectrometry relies on a vital step called «
charge derivatization» or using a permanently charged reagent to selectively trap the estrogens and isolate them from the lipids and proteins that could interfere with estrogen detection, Schug said.
These suspensions permit a variety of manipulations, such as sorting by length,
derivatization, and tethering to gold surfaces.
Noncovalent
derivatization: A longtime passion of Warner's (his license plate reads «NCD»), noncovalent derivatization is chemistry with a light touch.