Sentences with phrase «derived cell lineages»
By carefully guiding the cells» choices at each fork in the road, Loh and Chen were able to generate bone cell precursors that formed human bone when transplanted into laboratory mice and beating heart muscle cells, as well as 10 other mesodermal - derived cell lineages.
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It is generally accepted that paternally imprinted X inactivation occurs exclusively in extraembryonic lineages of mouse embryos, whereas cells of the embryo proper, derived from the inner cell mass (ICM), undergo only random X inactivation.
«To derive lineages, people use soluble growth factors to get the cells to differentiate,» explains Laura Kiessling, a UW - Madison professor of chemistry and biochemistry and stem cell expert.
The eye is composed of highly specialized tissues that are derived from a variety of cell lineages during development.
Foremost is that it is one of the first to show the benefits of using human iPS cell - derived renal lineage cells for cell therapy.
Recently, several observations suggested that, besides monocyte - derived macrophages, dendritic cells, a distinct myeloid lineage, also express PPARγ at high levels.
The second step will be to optimize culture conditions for the commitment of the iPS / hES cell - derived retinal precursors towards the photoreceptor lineage.
Transcription Factor - Induced Lineage Selection of Stem Cell - Derived Neural Progenitor Cells
His thesis was entitled «Quantitative description of microRNA target site occupancy in mouse embryonic stem cells and derived cells of neuronal lineage.»
We find that crustacean limb regeneration relies lineage - committed progenitor cells: muscles derive from satellite - like stem cells, whereas epidermis regenerates from existing epidermal cells.
Identification of common pathways mediating differentiation of bone marrow - and adipose tissue - derived human mesenchymal stem cells into three mesenchymal lineages.
Taken together, the evidence shows that NPC - derived iPS cells can differentiate spontaneously or be induced into specific lineages reproducibly in vitro.
Furthermore, human NSC - derived pluripotent stem cells can differentiate into all three germ lineages both in vitro and in vivo.
Through extensive examination, we have shown that human NSC - derived iPS cells are phenotypically identical to hESCs by all pluripotential markers analyzed and for their ability to differentiate into all three major germ lineages.
Embryonic stem (ES) cells are karyotypically normal, embryo - derived cell lines that are pluripotent, i.e. capable of generating all the cell types of the future organism, but not the extra-embryonic lineages.
In this way embryo - derived stem cell lines and ES cell differentiation may be providing access to potential «transition states,» required for lineage specification in vivo.
However, cells derived from the early epiblast are only able to contribute to embryonic lineages and not those derived from the PrEn [18]--[20], while PrEn cells can only contribute to their own lineage by colonizing the visceral and mostly parietal endoderm in chimera experiments [20]--[22].
While ES cells are derived from the ICM, they predominantly contribute to embryonic lineages.
Mouse embryonic stem cells derived from the epiblast contribute to the somatic lineages and the germline but are excluded from the extra-embryonic tissues that are derived from the trophectoderm and the primitive endoderm upon reintroduction to the blastocyst.
San Diego, CA (March 31, 2009)-- Novocell, Inc., a stem cell engineering company, today announced that it has received U.S. Patent 7,510,876 with claims covering human definitive endoderm cells, an essential cell for generating not only pancreatic type cells, which Novocell is developing for use as a cell therapy for diabetes, but also other endoderm lineage - derived tissues and organs such as lungs, intestine, liver, thymus and thyroid.
Bone marrow - derived mesenchymal stem cells (BMDMSC) are of particular interest in orthopedics, as cells in this lineage are involved in osteogenic differentiation of cells at the site of bone generation and regeneration.