This discovery, which earned Dr. Yamanaka the 2012 Nobel Prize in Physiology or Medicine, has revolutionized the fields of stem cell biology and regenerative medicine and has allowed scientists to model disease from patient -
derived cells in a dish, thus working towards a new era of personalized medicine.
Not exact matches
The disease model, described
in a new study by a UC San Francisco - led team, involves taking skin
cells from patients with the bone disease, reprogramming them
in a lab
dish to their embryonic state, and
deriving stem
cells from them.
In BRIC 17 - 1, cell cultures derived from thale cress plants are grown in Petri dishes and later examined to determine which genes are involved in certain cellular change
In BRIC 17 - 1,
cell cultures
derived from thale cress plants are grown
in Petri dishes and later examined to determine which genes are involved in certain cellular change
in Petri
dishes and later examined to determine which genes are involved
in certain cellular change
in certain cellular changes.
«The blood - brain barrier forms pretty early
in gestation, so the thyroid hormone, even from the mother, is probably not getting through the barrier and into the brain, likely leading to developmental deficits,» says Shusta, whose group was among the first to develop blood - brain barriers from patient -
derived stem
cells in the lab
dish.
Using cutting edge «disease
in a
dish» technologies, the researchers are now following up the leads discovered
in blood
cell lines
in neurons induced from stem
cells derived from the blood of PMDD patients —
in hopes of gaining a more direct window into the ESC / E (Z) complex's role
in the brain.
For these purpose, we explore and validate the use of
cell progenies
derived from pluripotent stem
cells to produce disease models
in a
dish, to screen for compounds (small molecules, biologicals, etc).